node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DVU_0665 | DVU_1876 | DVU_0665 | DVU_1876 | Nitrogen fixation protein nifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins; Belongs to the NifU family. | dnaJ protein, putative; Identified by similarity to SP:P08622; match to protein family HMM PF00226; match to protein family HMM PF01556. | 0.432 |
DVU_0665 | clpA | DVU_0665 | DVU_1602 | Nitrogen fixation protein nifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins; Belongs to the NifU family. | ATP-dependent Clp protease, ATP-binding subunit ClpA; Identified by similarity to SP:P15716; match to protein family HMM PF00004; match to protein family HMM PF02861; Belongs to the ClpA/ClpB family. | 0.514 |
DVU_0665 | clpB | DVU_0665 | DVU_1874 | Nitrogen fixation protein nifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins; Belongs to the NifU family. | ATP-dependent Clp protease, ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity). Belongs to [...] | 0.505 |
DVU_0665 | dnaJ | DVU_0665 | DVU_3243 | Nitrogen fixation protein nifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins; Belongs to the NifU family. | dnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...] | 0.410 |
DVU_0665 | dnaK | DVU_0665 | DVU_0811 | Nitrogen fixation protein nifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins; Belongs to the NifU family. | dnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.976 |
DVU_0665 | groEL | DVU_0665 | DVU_1976 | Nitrogen fixation protein nifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins; Belongs to the NifU family. | Chaperonin, 60 kDa; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.630 |
DVU_0665 | groES | DVU_0665 | DVU_1977 | Nitrogen fixation protein nifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins; Belongs to the NifU family. | Chaperonin, 10 kDa; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.649 |
DVU_0665 | grpE | DVU_0665 | DVU_0812 | Nitrogen fixation protein nifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins; Belongs to the NifU family. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.590 |
DVU_0665 | htpG | DVU_0665 | DVU_2643 | Nitrogen fixation protein nifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins; Belongs to the NifU family. | Heat shock protein HtpG; Molecular chaperone. Has ATPase activity; Belongs to the heat shock protein 90 family. | 0.580 |
DVU_1876 | DVU_0665 | DVU_1876 | DVU_0665 | dnaJ protein, putative; Identified by similarity to SP:P08622; match to protein family HMM PF00226; match to protein family HMM PF01556. | Nitrogen fixation protein nifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins; Belongs to the NifU family. | 0.432 |
DVU_1876 | clpA | DVU_1876 | DVU_1602 | dnaJ protein, putative; Identified by similarity to SP:P08622; match to protein family HMM PF00226; match to protein family HMM PF01556. | ATP-dependent Clp protease, ATP-binding subunit ClpA; Identified by similarity to SP:P15716; match to protein family HMM PF00004; match to protein family HMM PF02861; Belongs to the ClpA/ClpB family. | 0.814 |
DVU_1876 | clpB | DVU_1876 | DVU_1874 | dnaJ protein, putative; Identified by similarity to SP:P08622; match to protein family HMM PF00226; match to protein family HMM PF01556. | ATP-dependent Clp protease, ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity). Belongs to [...] | 0.930 |
DVU_1876 | dnaK | DVU_1876 | DVU_0811 | dnaJ protein, putative; Identified by similarity to SP:P08622; match to protein family HMM PF00226; match to protein family HMM PF01556. | dnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.995 |
DVU_1876 | groEL | DVU_1876 | DVU_1976 | dnaJ protein, putative; Identified by similarity to SP:P08622; match to protein family HMM PF00226; match to protein family HMM PF01556. | Chaperonin, 60 kDa; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.781 |
DVU_1876 | groES | DVU_1876 | DVU_1977 | dnaJ protein, putative; Identified by similarity to SP:P08622; match to protein family HMM PF00226; match to protein family HMM PF01556. | Chaperonin, 10 kDa; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.690 |
DVU_1876 | grpE | DVU_1876 | DVU_0812 | dnaJ protein, putative; Identified by similarity to SP:P08622; match to protein family HMM PF00226; match to protein family HMM PF01556. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.981 |
DVU_1876 | hrcA | DVU_1876 | DVU_0813 | dnaJ protein, putative; Identified by similarity to SP:P08622; match to protein family HMM PF00226; match to protein family HMM PF01556. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.907 |
DVU_1876 | htpG | DVU_1876 | DVU_2643 | dnaJ protein, putative; Identified by similarity to SP:P08622; match to protein family HMM PF00226; match to protein family HMM PF01556. | Heat shock protein HtpG; Molecular chaperone. Has ATPase activity; Belongs to the heat shock protein 90 family. | 0.902 |
clpA | DVU_0665 | DVU_1602 | DVU_0665 | ATP-dependent Clp protease, ATP-binding subunit ClpA; Identified by similarity to SP:P15716; match to protein family HMM PF00004; match to protein family HMM PF02861; Belongs to the ClpA/ClpB family. | Nitrogen fixation protein nifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins; Belongs to the NifU family. | 0.514 |
clpA | DVU_1876 | DVU_1602 | DVU_1876 | ATP-dependent Clp protease, ATP-binding subunit ClpA; Identified by similarity to SP:P15716; match to protein family HMM PF00004; match to protein family HMM PF02861; Belongs to the ClpA/ClpB family. | dnaJ protein, putative; Identified by similarity to SP:P08622; match to protein family HMM PF00226; match to protein family HMM PF01556. | 0.814 |