STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aprAAdenylyl-sulphate reductase, alpha subunit; Identified by similarity to GP:7109235; match to protein family HMM TIGR02061. (664 aa)    
Predicted Functional Partners:
aprB
Adenylylsulphate reductase, beta subunit; Identified by similarity to GP:7109234; match to protein family HMM PF00037; match to protein family HMM TIGR02060.
 
 0.999
dsvA
Dissimilatory sulfite reductase alpha subunit; Part of the complex that catalyzes the reduction of sulfite to sulfide. The alpha and beta subunits may have arisen by gene duplication. They both bind 2 iron-sulfur clusters, but the alpha subunit seems to be catalytically inactive, due to substitutions along the putative substrate access channel, and because it binds sirohydrochlorin (the dematallated form of siroheme) instead of siroheme.
 
 
 0.995
dvsB
Dissimilatory sulfite reductase beta subunit; Catalyzes the reduction of sulfite to sulfide. This is the terminal oxidation reaction in sulfate respiration, a process catalyzed by the sulfate-reducing bacteria.
 
 
 0.995
sat
Sulfate adenylyltransferase; Identified by similarity to SP:P56864; match to protein family HMM PF01747; match to protein family HMM TIGR00339.
 
 
 0.990
sucCD
succinyl-CoA synthase, beta/alpha subunits; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.973
frdC
Fumarate reductase, cytochrome b subunit; Identified by similarity to SP:P17413.
  
 0.969
poR
Pyruvate-ferredoxin oxidoreductase; Identified by similarity to GP:1770208; match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855.
  
 
 0.968
DVU_0849
Heterodisulfide reductase, iron-sulfur-binding subunit, putative; Identified by match to protein family HMM PF00037; match to protein family HMM PF02662.
 
  
 0.964
DVU_0848
Heterodisulfide reductase, putative; Identified by similarity to GP:1890204.
 
  
 0.947
DVU_2674
Succinate dehydrogenase and fumarate reductase iron-sulfur protein; Identified by match to protein family HMM PF00037; match to protein family HMM PF00111; match to protein family HMM TIGR00384; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 0.937
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.