STRINGSTRING
aprA protein (Desulfovibrio vulgaris Hildenborough) - STRING interaction network
"aprA" - Adenylyl-sulphate reductase, alpha subunit in Desulfovibrio vulgaris Hildenborough
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aprAAdenylyl-sulphate reductase, alpha subunit; Identified by similarity to GP-7109235; match to protein family HMM TIGR02061 (664 aa)    
Predicted Functional Partners:
aprB
Adenylylsulphate reductase, beta subunit; Identified by similarity to GP-7109234; match to protein family HMM PF00037; match to protein family HMM TIGR02060 (167 aa)
 
  0.999
dsvA
Sulfite reductase, dissimilatory-type subunit alpha; Part of the complex that catalyzes the reduction of sulfite to sulfide. The alpha and beta subunits may have arisen by gene duplication. They both bind 2 iron-sulfur clusters, but the alpha subunit seems to be catalytically inactive, due to substitutions along the putative substrate access channel, and because it binds sirohydrochlorin (the dematallated form of siroheme) instead of siroheme (437 aa)
 
   
  0.996
sat
Sulfate adenylyltransferase; Identified by similarity to SP-P56864; match to protein family HMM PF01747; match to protein family HMM TIGR00339 (427 aa)
 
 
  0.996
dvsB
Sulfite reductase, dissimilatory-type subunit beta; Catalyzes the reduction of sulfite to sulfide. This is the terminal oxidation reaction in sulfate respiration, a process catalyzed by the sulfate-reducing bacteria (381 aa)
 
   
  0.994
dsvD
Protein DsvD; May play an essential role in dissimilatory sulfite reduction (78 aa)
   
   
  0.970
DVU_0849
Heterodisulfide reductase, iron-sulfur-binding subunit, putative; Identified by match to protein family HMM PF00037; match to protein family HMM PF02662 (758 aa)
 
 
      0.970
sucCD
Succinate--CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit (709 aa)
   
 
  0.968
DVU_0253
Oxidoreductase, FAD/iron-sulfur cluster-binding domain protein; Identified by match to protein family HMM PF00037; match to protein family HMM PF01565; match to protein family HMM PF02913 (941 aa)
   
 
  0.934
DVU_0173
Thiosulfate reductase, putative; Identified by similarity to SP-P37600; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879 (733 aa)
   
 
  0.924
DVU_1566
Phosphoadenosine phosphosulfate reductase, putative; Identified by match to protein family HMM PF01507 (255 aa)
   
 
  0.911
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris Hildenborough, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
Server load: low (16%) [HD]