STRINGSTRING
hemB protein (Desulfovibrio vulgaris Hildenborough) - STRING interaction network
"hemB" - Porphobilinogen synthase in Desulfovibrio vulgaris Hildenborough
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemBPorphobilinogen synthase; Identified by match to protein family HMM PF00490 (330 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps; Belongs to the HMBS family (315 aa)
 
  0.996
DVU_0734
Uroporphyrinogen III synthase/methyltransferase; Identified by similarity to GP-12655814; match to protein family HMM PF00590; match to protein family HMM PF02602; match to protein family HMM TIGR01369; match to protein family HMM TIGR01469 (503 aa)
 
 
  0.992
hemL
Glutamate-1-semialdehyde 2,1-aminomutase; Identified by similarity to SP-P30949; match to protein family HMM PF00202; match to protein family HMM TIGR00713; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily (423 aa)
 
 
  0.991
hemA
Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA); Belongs to the glutamyl-tRNA reductase family (440 aa)
 
   
  0.937
DVU_0857
Radical SAM domain protein; Identified by match to protein family HMM PF04055 (393 aa)
              0.886
atpD
ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family (470 aa)
 
 
 
  0.790
DVU_0855
Radical SAM domain protein; Identified by match to protein family HMM PF04055 (367 aa)
              0.722
DVU_0854
NirD protein, putative; Identified by similarity to SP-Q52522 (176 aa)
              0.722
DVU_0973
4-hydroxybenzoate octaprenyltransferase, putative; Identified by match to protein family HMM PF01040; match to protein family HMM TIGR01475 (289 aa)
   
   
  0.635
DVU_2399
Hydrogenase, putative; Identified by similarity to GP-21327886; match to protein family HMM PF00175; match to protein family HMM PF00970 (283 aa)
   
   
  0.603
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris Hildenborough, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
Server load: low (12%) [HD]