STRINGSTRING
aroC protein (Desulfovibrio vulgaris Hildenborough) - STRING interaction network
"aroC" - Chorismate synthase in Desulfovibrio vulgaris Hildenborough
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system (354 aa)    
Predicted Functional Partners:
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate; Belongs to the EPSP synthase family (439 aa)
 
 
  0.986
DVU_0462
Chorismate mutase/prephenate dehydratase; Identified by similarity to SP-P07022; match to protein family HMM PF00800; match to protein family HMM PF01817; match to protein family HMM PF01842; match to protein family HMM TIGR01807 (391 aa)
 
  0.985
aroK-1
Shikimate kinase; Identified by similarity to SP-P10880; match to protein family HMM PF01202 (175 aa)
 
   
  0.963
trpG
Anthranilate synthase, glutamine amidotransferase component; Identified by similarity to SP-Q08654; match to protein family HMM PF00117; match to protein family HMM TIGR00566 (209 aa)
 
 
  0.960
DVU_0465
Anthranilate synthase, component I; Identified by similarity to SP-O66849; match to protein family HMM PF00425; match to protein family HMM PF04715 (532 aa)
 
 
  0.951
aroE
Shikimate dehydrogenase (NADP(+)); Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) (301 aa)
 
 
  0.936
pabA
Para-aminobenzoate/anthranilate synthase glutamine amidotransferase; Identified by similarity to SP-P28819; match to protein family HMM PF00117 (184 aa)
 
 
  0.925
pabB
Para-aminobenzoate synthase, component I; Identified by match to protein family HMM PF00425 (334 aa)
 
 
  0.911
aroK-2
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family (180 aa)
 
   
  0.859
phoU
Phosphate-specific transport system accessory protein PhoU; Plays a role in the regulation of phosphate uptake (221 aa)
     
 
  0.838
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris Hildenborough, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
Server load: low (11%) [HD]