STRINGSTRING
lipB protein (Desulfovibrio vulgaris Hildenborough) - STRING interaction network
"lipB" - Octanoyltransferase in Desulfovibrio vulgaris Hildenborough
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lipBOctanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (218 aa)    
Predicted Functional Partners:
lipA
Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (298 aa)
 
  0.999
DVU_0908
annotation not available (543 aa)
              0.911
DVU_0907
Conserved domain protein; Identified by similarity to OMNI-NTL01BM0443 (979 aa)
   
   
  0.896
DVU_2563
Beta-ketoacyl synthase, putative; Identified by match to protein family HMM PF00109; match to protein family HMM PF02801; Belongs to the beta-ketoacyl-ACP synthases family (482 aa)
     
    0.821
fabF
3-oxoacyl-[acyl-carrier-protein] synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP; Belongs to the beta-ketoacyl-ACP synthases family (415 aa)
     
    0.821
fabI
Enoyl-[acyl-carrier-protein] reductase [NADH]; Identified by similarity to SP-P29132; match to protein family HMM PF00106 (254 aa)
       
    0.806
DVU_0257
Acetyltransferase, GNAT family; Identified by match to protein family HMM PF00583 (154 aa)
 
 
        0.765
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (127 aa)
   
 
  0.687
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis (76 aa)
     
 
  0.585
birA
Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor (330 aa)
         
  0.570
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris Hildenborough, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
Server load: low (14%) [HD]