node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DVU_0982 | DVU_0983 | DVU_0982 | DVU_0983 | PHP domain protein; Identified by match to protein family HMM PF02231; match to protein family HMM PF02811. | Conserved hypothetical protein; Identified by similarity to SP:Q50604; match to protein family HMM PF02577. | 0.808 |
DVU_0982 | DVU_0985 | DVU_0982 | DVU_0985 | PHP domain protein; Identified by match to protein family HMM PF02231; match to protein family HMM PF02811. | Hypothetical protein; Identified by Glimmer2; putative. | 0.580 |
DVU_0982 | miaB | DVU_0982 | DVU_0984 | PHP domain protein; Identified by match to protein family HMM PF02231; match to protein family HMM PF02811. | tRNA-i(6)A37 modification enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | 0.803 |
DVU_0983 | DVU_0982 | DVU_0983 | DVU_0982 | Conserved hypothetical protein; Identified by similarity to SP:Q50604; match to protein family HMM PF02577. | PHP domain protein; Identified by match to protein family HMM PF02231; match to protein family HMM PF02811. | 0.808 |
DVU_0983 | DVU_0985 | DVU_0983 | DVU_0985 | Conserved hypothetical protein; Identified by similarity to SP:Q50604; match to protein family HMM PF02577. | Hypothetical protein; Identified by Glimmer2; putative. | 0.577 |
DVU_0983 | miaB | DVU_0983 | DVU_0984 | Conserved hypothetical protein; Identified by similarity to SP:Q50604; match to protein family HMM PF02577. | tRNA-i(6)A37 modification enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | 0.803 |
DVU_0985 | DVU_0982 | DVU_0985 | DVU_0982 | Hypothetical protein; Identified by Glimmer2; putative. | PHP domain protein; Identified by match to protein family HMM PF02231; match to protein family HMM PF02811. | 0.580 |
DVU_0985 | DVU_0983 | DVU_0985 | DVU_0983 | Hypothetical protein; Identified by Glimmer2; putative. | Conserved hypothetical protein; Identified by similarity to SP:Q50604; match to protein family HMM PF02577. | 0.577 |
DVU_0985 | miaB | DVU_0985 | DVU_0984 | Hypothetical protein; Identified by Glimmer2; putative. | tRNA-i(6)A37 modification enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | 0.572 |
DVU_3057 | miaB | DVU_3057 | DVU_0984 | Oxygen-independent coproporphyrinogen III oxidase, putative; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | tRNA-i(6)A37 modification enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | 0.622 |
DVU_3057 | rlmN | DVU_3057 | DVU_2904 | Oxygen-independent coproporphyrinogen III oxidase, putative; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Radical SAM enzyme, Cfr family; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.706 |
bioB | lipB | DVU_2558 | DVU_0906 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.692 |
bioB | miaB | DVU_2558 | DVU_0984 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | tRNA-i(6)A37 modification enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | 0.751 |
lipB | bioB | DVU_0906 | DVU_2558 | Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.692 |
lipB | miaB | DVU_0906 | DVU_0984 | Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | tRNA-i(6)A37 modification enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | 0.599 |
miaA | miaB | DVU_1533 | DVU_0984 | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | tRNA-i(6)A37 modification enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | 0.847 |
miaB | DVU_0982 | DVU_0984 | DVU_0982 | tRNA-i(6)A37 modification enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | PHP domain protein; Identified by match to protein family HMM PF02231; match to protein family HMM PF02811. | 0.803 |
miaB | DVU_0983 | DVU_0984 | DVU_0983 | tRNA-i(6)A37 modification enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | Conserved hypothetical protein; Identified by similarity to SP:Q50604; match to protein family HMM PF02577. | 0.803 |
miaB | DVU_0985 | DVU_0984 | DVU_0985 | tRNA-i(6)A37 modification enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | Hypothetical protein; Identified by Glimmer2; putative. | 0.572 |
miaB | DVU_3057 | DVU_0984 | DVU_3057 | tRNA-i(6)A37 modification enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | Oxygen-independent coproporphyrinogen III oxidase, putative; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.622 |