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glyA protein (Desulfovibrio vulgaris Hildenborough) - STRING interaction network
"glyA" - Serine hydroxymethyltransferase in Desulfovibrio vulgaris Hildenborough
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experimentally determined
Predicted Interactions
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gene co-occurrence
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textmining
co-expression
protein homology
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glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism; Belongs to the SHMT family (412 aa)    
Predicted Functional Partners:
gcvT
Glycine cleavage system T protein; Identified by match to protein family HMM PF01571; match to protein family HMM TIGR00528 (362 aa)
  0.998
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (127 aa)
   
 
  0.992
folD
Bifunctional protein FolD; Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (286 aa)
 
 
  0.992
fmt
Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus (330 aa)
   
 
  0.987
gcvPB
Glycine dehydrogenase (aminomethyl-transferring); Identified by similarity to SP-P54377; Belongs to the GcvP family (481 aa)
 
 
  0.986
DVU_1580
Ribose 5-phosphate isomerase, putative; Identified by match to protein family HMM PF02502; match to protein family HMM TIGR00689; match to protein family HMM TIGR01120 (147 aa)
   
 
  0.986
DVU_3206
Phosphoribosylaminoimidazolecarboxamide formyltransferase, putative; Identified by similarity to SP-P12048; match to protein family HMM PF01808 (510 aa)
   
  0.983
thyX
Flavin-dependent thymidylate synthase; Catalyzes the reductive methylation of 2’-deoxyuridine- 5’-monophosphate (dUMP) to 2’-deoxythymidine-5’-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant (245 aa)
     
  0.973
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate (225 aa)
 
 
  0.970
ltaE
Threonine aldolase, low-specificity; Identified by similarity to SP-O50584 (340 aa)
     
  0.969
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris Hildenborough, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
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