fabH protein (Desulfovibrio vulgaris Hildenborough)

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fabH

3-oxoacyl-[acyl-carrier-protein] synthase 3; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and/or straight-chain of fatty acids; Belongs to the FabH family (330 aa)

Predicted Functional Partners:

fabD

0.999

fabF

0.997

fabG

0.994

plsX

0.994

DVU_2563

0.991

DVU_2225

0.988

fabZ

0.958

DVU_3137

0.940

DVU_2561

0.939

DVU_3065

0.920

Your Current Organism:

Desulfovibrio vulgaris Hildenborough

NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris Hildenborough, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DVU_2225	DVU_2561	DVU_2225	DVU_2561	annotation not available	Oxidoreductase, short chain dehydrogenase/reductase family; Identified by match to protein family HMM PF00106	0.674
DVU_2225	DVU_2563	DVU_2225	DVU_2563	annotation not available	Beta-ketoacyl synthase, putative; Identified by match to protein family HMM PF00109; match to protein family HMM PF02801; Belongs to the beta-ketoacyl-ACP synthases family	0.936
DVU_2225	DVU_3137	DVU_2225	DVU_3137	annotation not available	Oxidoreductase, short chain dehydrogenase/reductase family; Identified by match to protein family HMM PF00106	0.674
DVU_2225	fabD	DVU_2225	DVU_1249	annotation not available	Malonyl CoA-acyl carrier protein transacylase; Identified by match to protein family HMM PF00698; match to protein family HMM TIGR00128	0.990
DVU_2225	fabF	DVU_2225	DVU_1204	annotation not available	3-oxoacyl-[acyl-carrier-protein] synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP; Belongs to the beta-ketoacyl-ACP synthases family	0.959
DVU_2225	fabG	DVU_2225	DVU_1206	annotation not available	3-oxoacyl-(Acyl-carrier-protein) reductase; Identified by match to protein family HMM PF00106; match to protein family HMM TIGR01830	0.716
DVU_2225	fabH	DVU_2225	DVU_1207	annotation not available	3-oxoacyl-[acyl-carrier-protein] synthase 3; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and/or straight-chain of fatty acids; Belongs to the FabH family	0.988
DVU_2225	fabZ	DVU_2225	DVU_2368	annotation not available	3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	0.856
DVU_2225	plsX	DVU_2225	DVU_1208	annotation not available	Phosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	0.703
DVU_2561	DVU_2225	DVU_2561	DVU_2225	Oxidoreductase, short chain dehydrogenase/reductase family; Identified by match to protein family HMM PF00106	annotation not available	0.674
DVU_2561	DVU_2563	DVU_2561	DVU_2563	Oxidoreductase, short chain dehydrogenase/reductase family; Identified by match to protein family HMM PF00106	Beta-ketoacyl synthase, putative; Identified by match to protein family HMM PF00109; match to protein family HMM PF02801; Belongs to the beta-ketoacyl-ACP synthases family	0.986
DVU_2561	DVU_3137	DVU_2561	DVU_3137	Oxidoreductase, short chain dehydrogenase/reductase family; Identified by match to protein family HMM PF00106	Oxidoreductase, short chain dehydrogenase/reductase family; Identified by match to protein family HMM PF00106	0.800
DVU_2561	fabD	DVU_2561	DVU_1249	Oxidoreductase, short chain dehydrogenase/reductase family; Identified by match to protein family HMM PF00106	Malonyl CoA-acyl carrier protein transacylase; Identified by match to protein family HMM PF00698; match to protein family HMM TIGR00128	0.893
DVU_2561	fabF	DVU_2561	DVU_1204	Oxidoreductase, short chain dehydrogenase/reductase family; Identified by match to protein family HMM PF00106	3-oxoacyl-[acyl-carrier-protein] synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP; Belongs to the beta-ketoacyl-ACP synthases family	0.973
DVU_2561	fabG	DVU_2561	DVU_1206	Oxidoreductase, short chain dehydrogenase/reductase family; Identified by match to protein family HMM PF00106	3-oxoacyl-(Acyl-carrier-protein) reductase; Identified by match to protein family HMM PF00106; match to protein family HMM TIGR01830	0.814
DVU_2561	fabH	DVU_2561	DVU_1207	Oxidoreductase, short chain dehydrogenase/reductase family; Identified by match to protein family HMM PF00106	3-oxoacyl-[acyl-carrier-protein] synthase 3; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and/or straight-chain of fatty acids; Belongs to the FabH family	0.939
DVU_2561	fabZ	DVU_2561	DVU_2368	Oxidoreductase, short chain dehydrogenase/reductase family; Identified by match to protein family HMM PF00106	3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	0.912
DVU_2563	DVU_2225	DVU_2563	DVU_2225	Beta-ketoacyl synthase, putative; Identified by match to protein family HMM PF00109; match to protein family HMM PF02801; Belongs to the beta-ketoacyl-ACP synthases family	annotation not available	0.936
DVU_2563	DVU_2561	DVU_2563	DVU_2561	Beta-ketoacyl synthase, putative; Identified by match to protein family HMM PF00109; match to protein family HMM PF02801; Belongs to the beta-ketoacyl-ACP synthases family	Oxidoreductase, short chain dehydrogenase/reductase family; Identified by match to protein family HMM PF00106	0.986
DVU_2563	DVU_3065	DVU_2563	DVU_3065	Beta-ketoacyl synthase, putative; Identified by match to protein family HMM PF00109; match to protein family HMM PF02801; Belongs to the beta-ketoacyl-ACP synthases family	Identified by match to protein family HMM PF00501	0.917

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