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gcvPA protein (Desulfovibrio vulgaris Hildenborough) - STRING interaction network
"gcvPA" - Probable glycine dehydrogenase in Desulfovibrio vulgaris Hildenborough
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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gcvPAProbable glycine dehydrogenase (decarboxylating) subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. N-terminal subunit subfamily (443 aa)    
Predicted Functional Partners:
gcvT
Glycine cleavage system T protein; Identified by match to protein family HMM PF01571; match to protein family HMM TIGR00528 (362 aa)
  0.999
gcvPB
Glycine dehydrogenase (aminomethyl-transferring); Identified by similarity to SP-P54377; Belongs to the GcvP family (481 aa)
0.999
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (127 aa)
  0.999
lpdA
2-oxoglutarate dehydrogenase, E3 component, lipoamide dehydrogenase; Identified by similarity to SP-O34324; match to protein family HMM PF00070; match to protein family HMM PF02852; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family (456 aa)
 
   
  0.993
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism; Belongs to the SHMT family (412 aa)
 
 
  0.968
ltaE
Threonine aldolase, low-specificity; Identified by similarity to SP-O50584 (340 aa)
       
  0.911
DVU_3121
Aminotransferase, class V; Identified by match to protein family HMM PF00266 (376 aa)
         
    0.900
putA
Bifunctional protein PutA; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family (1006 aa)
   
  0.838
DVU_0964
Identified by match to protein family HMM PF00208 (997 aa)
         
    0.800
glnA
Glutamine synthetase, type I; Identified by similarity to SP-P12425; match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653 (447 aa)
         
  0.617
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris Hildenborough, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
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