DVU_1584 protein (Desulfovibrio vulgaris Hildenborough)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

DVU_1584

Sigma 70 family protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (356 aa)

Predicted Functional Partners:

rpoB

0.952

rpoZ

0.941

rpoA

0.936

DVU_1572

0.906

rpoC

0.888

dnaJ

0.857

nusA

0.845

DVU_1583

0.842

dnaK

0.840

DVU_1582

0.837

Your Current Organism:

Desulfovibrio vulgaris Hildenborough

NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DVU_1572	DVU_1584	DVU_1572	DVU_1584	Transcriptional regulator, CarD family; Identified by match to protein family HMM PF02559.	Sigma 70 family protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	0.906
DVU_1572	rpoA	DVU_1572	DVU_1329	Transcriptional regulator, CarD family; Identified by match to protein family HMM PF02559.	DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.860
DVU_1572	rpoB	DVU_1572	DVU_2928	Transcriptional regulator, CarD family; Identified by match to protein family HMM PF02559.	DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.874
DVU_1572	rpoC	DVU_1572	DVU_2929	Transcriptional regulator, CarD family; Identified by match to protein family HMM PF02559.	DNA-directed RNA polymerase, beta prime subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.870
DVU_1572	rpoZ	DVU_1572	DVU_3242	Transcriptional regulator, CarD family; Identified by match to protein family HMM PF02559.	DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.920
DVU_1582	DVU_1583	DVU_1582	DVU_1583	Hypothetical protein; Identified by Glimmer2; putative.	TPR domain protein; Identified by match to protein family HMM PF00515.	0.841
DVU_1582	DVU_1584	DVU_1582	DVU_1584	Hypothetical protein; Identified by Glimmer2; putative.	Sigma 70 family protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	0.837
DVU_1583	DVU_1582	DVU_1583	DVU_1582	TPR domain protein; Identified by match to protein family HMM PF00515.	Hypothetical protein; Identified by Glimmer2; putative.	0.841
DVU_1583	DVU_1584	DVU_1583	DVU_1584	TPR domain protein; Identified by match to protein family HMM PF00515.	Sigma 70 family protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	0.842
DVU_1584	DVU_1572	DVU_1584	DVU_1572	Sigma 70 family protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	Transcriptional regulator, CarD family; Identified by match to protein family HMM PF02559.	0.906
DVU_1584	DVU_1582	DVU_1584	DVU_1582	Sigma 70 family protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	Hypothetical protein; Identified by Glimmer2; putative.	0.837
DVU_1584	DVU_1583	DVU_1584	DVU_1583	Sigma 70 family protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	TPR domain protein; Identified by match to protein family HMM PF00515.	0.842
DVU_1584	dnaJ	DVU_1584	DVU_3243	Sigma 70 family protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	dnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...]	0.857
DVU_1584	dnaK	DVU_1584	DVU_0811	Sigma 70 family protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	dnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.840
DVU_1584	nusA	DVU_1584	DVU_0510	Sigma 70 family protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	N utilization substance protein A; Participates in both transcription termination and antitermination.	0.845
DVU_1584	rpoA	DVU_1584	DVU_1329	Sigma 70 family protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.936
DVU_1584	rpoB	DVU_1584	DVU_2928	Sigma 70 family protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.952
DVU_1584	rpoC	DVU_1584	DVU_2929	Sigma 70 family protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	DNA-directed RNA polymerase, beta prime subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.888
DVU_1584	rpoZ	DVU_1584	DVU_3242	Sigma 70 family protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.941
dnaJ	DVU_1584	DVU_3243	DVU_1584	dnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...]	Sigma 70 family protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	0.857

page 1 of 4

Server load: medium (52%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Co-occurrence

Textmining

Co-expression

© STRING Consortium 2026

Credits

Access

Info

About