STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
xerC-2Site-specific recombinase, phage integrase family; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (474 aa)    
Predicted Functional Partners:
DVU_2067
GGDEF domain protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00990; match to protein family HMM TIGR00254.
     
 0.868
DVU_2068
HD domain protein; Identified by similarity to OMNI:TM0854; match to protein family HMM PF01966.
       0.800
DVU_2069
DNA processing protein DprA, putative; Identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732.
 
   
 0.789
DVU_1667
Identified by match to protein family HMM PF01580.
 
  
 0.660
prfC
Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
   
  
 0.649
recR
Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
  
  
 0.646
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
  
 0.642
DVU_0408
Response regulator/sensory box/GGDEF domain/EAL domain protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00563; match to protein family HMM PF00785; match to protein family HMM PF00989; match to protein family HMM PF00990; match to protein family HMM TIGR00229; match to protein family HMM TIGR00254.
     
 0.593
DVU_3360
Identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; Belongs to the ParB family.
  
  
 0.586
DVU_1757
Site-specific recombinase, phage integrase family; Identified by match to protein family HMM PF00589; Belongs to the 'phage' integrase family.
  
  
 0.584
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
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