Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
DVU_2069DNA processing protein DprA, putative; Identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732. (663 aa)    
Predicted Functional Partners:
DVU_2768
comF family protein; Identified by similarity to SP:P31773.
 
 
 0.939
DVU_3257
DNA internalization-related competence protein ComEC/Rec2; Identified by similarity to SP:P39695; match to protein family HMM TIGR00360.
 
  
 0.901
pppA
Type IV prepilin-like proteins leader peptidase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
  
  
 0.872
DVU_0710
Competence protein comM, putative; Identified by similarity to SP:P45049; match to protein family HMM PF01078; match to protein family HMM TIGR00368.
 
 
 0.853
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 0.832
cpoB-2
TPR domain protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.
  
    0.829
ssb
Single-strand binding protein; Identified by similarity to SP:P02339; match to protein family HMM PF00436; match to protein family HMM TIGR00621.
 
  
 0.749
radC
DNA repair protein RadC; Identified by similarity to SP:P25531; match to protein family HMM PF04002; match to protein family HMM TIGR00608; Belongs to the UPF0758 family.
  
  
 0.697
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
   
 
 0.669
DVU_1272
General secretion pathway protein E, putative; Identified by similarity to SP:P37093; match to protein family HMM PF00437; match to protein family HMM PF05157.
  
  
 0.649
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
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