STRINGSTRING
thiS protein (Desulfovibrio vulgaris Hildenborough) - STRING interaction network
"thiS" - Thiamine biosynthesis protein ThiS in Desulfovibrio vulgaris Hildenborough
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiSThiamine biosynthesis protein ThiS; Identified by match to protein family HMM PF02597; match to protein family HMM TIGR01683 (66 aa)    
Predicted Functional Partners:
DVU_2092
Identified by match to protein family HMM PF00899 (213 aa)
 
  0.991
thiG
Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (265 aa)
 
 
  0.983
DVU_0643
ThiF protein, putative; Identified by similarity to SP-P30138; match to protein family HMM PF00899 (230 aa)
   
  0.940
thiH
ThiH protein; Identified by similarity to SP-P30140; match to protein family HMM PF04055 (444 aa)
 
        0.908
thiE-1
Thiamine-phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (226 aa)
   
   
  0.771
thiC
Thiamine biosynthesis protein ThiC; Identified by match to protein family HMM PF01964; match to protein family HMM TIGR00190 (429 aa)
   
   
  0.606
DVU_3241
Uncharacterized protein; Identified by similarity to OMNI-NTL03CP0990; match to protein family HMM PF01171; Belongs to the TtcA family (248 aa)
     
 
  0.532
tilS
tRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine; Belongs to the tRNA(Ile)-lysidine synthase family (390 aa)
     
 
  0.532
DVU_0135
Uncharacterized protein; Identified by similarity to OMNI-NTL01AA00924; Belongs to the TtcA family (303 aa)
     
 
  0.532
thiE-2
Thiamine-phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP); Belongs to the thiamine-phosphate synthase family (219 aa)
   
   
  0.531
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris Hildenborough, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
Server load: low (15%) [HD]