Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
DVU_2250Identified by match to protein family HMM PF00501. (551 aa)    
Predicted Functional Partners:
DVU_2251
Identified by match to protein family HMM PF01381.
 
 
 0.989
poR
Pyruvate-ferredoxin oxidoreductase; Identified by similarity to GP:1770208; match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855.
  
 0.971
pta
Phosphate acetyltransferase; Involved in acetate metabolism; In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.970
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
     
 0.961
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
   
 0.940
DVU_1834
Pyruvate carboxylase, putative; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 
 0.933
DVU_2225
acetyl-CoA carboxylase, carboxyl transferase, alpha/beta subunit.
    
 0.930
DVU_1914
2-isopropylmalate synthase/homocitrate synthase family protein; Identified by match to protein family HMM PF00682; match to protein family HMM TIGR00977; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.928
porA
Pyruvate ferredoxin oxidoreductase, alpha subunit; Identified by similarity to GP:43498; match to protein family HMM PF01558; match to protein family HMM PF01855.
  
 
 0.924
DVU_3349
Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain protein; Identified by match to protein family HMM PF01855.
 
 
 0.924
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
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