node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DVU_1515 | DVU_1746 | DVU_1515 | DVU_1746 | Type II DNA modification methyltransferase, putative; Identified by match to protein family HMM PF00145; match to protein family HMM TIGR00675. | C-5 cytosine-specific DNA methylase family protein; Identified by match to protein family HMM PF00145; match to protein family HMM TIGR00675; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.929 |
DVU_1515 | DVU_2842 | DVU_1515 | DVU_2842 | Type II DNA modification methyltransferase, putative; Identified by match to protein family HMM PF00145; match to protein family HMM TIGR00675. | Type II DNA modification methyltransferase, putative; Identified by similarity to SP:P11876; match to protein family HMM PF00145; match to protein family HMM TIGR00675. | 0.929 |
DVU_1515 | ahcY | DVU_1515 | DVU_0607 | Type II DNA modification methyltransferase, putative; Identified by match to protein family HMM PF00145; match to protein family HMM TIGR00675. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.905 |
DVU_1515 | metK | DVU_1515 | DVU_2449 | Type II DNA modification methyltransferase, putative; Identified by match to protein family HMM PF00145; match to protein family HMM TIGR00675. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.917 |
DVU_1585 | ahcY | DVU_1585 | DVU_0607 | Vitamin B12-dependent methionine synthase family protein; Identified by similarity to SP:P37586; match to protein family HMM PF00809; match to protein family HMM PF02310; match to protein family HMM PF02574; match to protein family HMM PF02607. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.960 |
DVU_1585 | glyA | DVU_1585 | DVU_1203 | Vitamin B12-dependent methionine synthase family protein; Identified by similarity to SP:P37586; match to protein family HMM PF00809; match to protein family HMM PF02310; match to protein family HMM PF02574; match to protein family HMM PF02607. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism; Belongs to the SHMT family. | 0.950 |
DVU_1585 | guaA | DVU_1585 | DVU_1043 | Vitamin B12-dependent methionine synthase family protein; Identified by similarity to SP:P37586; match to protein family HMM PF00809; match to protein family HMM PF02310; match to protein family HMM PF02574; match to protein family HMM PF02607. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.610 |
DVU_1585 | metE | DVU_1585 | DVU_3371 | Vitamin B12-dependent methionine synthase family protein; Identified by similarity to SP:P37586; match to protein family HMM PF00809; match to protein family HMM PF02310; match to protein family HMM PF02574; match to protein family HMM PF02607. | 5-methyltetrahydropteroyltriglutamate- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.985 |
DVU_1585 | metF | DVU_1585 | DVU_0997 | Vitamin B12-dependent methionine synthase family protein; Identified by similarity to SP:P37586; match to protein family HMM PF00809; match to protein family HMM PF02310; match to protein family HMM PF02574; match to protein family HMM PF02607. | 5,10-methylenetetrahydrofolate reductase; Identified by match to protein family HMM PF02219; match to protein family HMM TIGR00676; Belongs to the methylenetetrahydrofolate reductase family. | 0.998 |
DVU_1585 | metK | DVU_1585 | DVU_2449 | Vitamin B12-dependent methionine synthase family protein; Identified by similarity to SP:P37586; match to protein family HMM PF00809; match to protein family HMM PF02310; match to protein family HMM PF02574; match to protein family HMM PF02607. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.964 |
DVU_1746 | DVU_1515 | DVU_1746 | DVU_1515 | C-5 cytosine-specific DNA methylase family protein; Identified by match to protein family HMM PF00145; match to protein family HMM TIGR00675; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | Type II DNA modification methyltransferase, putative; Identified by match to protein family HMM PF00145; match to protein family HMM TIGR00675. | 0.929 |
DVU_1746 | DVU_2842 | DVU_1746 | DVU_2842 | C-5 cytosine-specific DNA methylase family protein; Identified by match to protein family HMM PF00145; match to protein family HMM TIGR00675; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | Type II DNA modification methyltransferase, putative; Identified by similarity to SP:P11876; match to protein family HMM PF00145; match to protein family HMM TIGR00675. | 0.930 |
DVU_1746 | ahcY | DVU_1746 | DVU_0607 | C-5 cytosine-specific DNA methylase family protein; Identified by match to protein family HMM PF00145; match to protein family HMM TIGR00675; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.906 |
DVU_1746 | metK | DVU_1746 | DVU_2449 | C-5 cytosine-specific DNA methylase family protein; Identified by match to protein family HMM PF00145; match to protein family HMM TIGR00675; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.917 |
DVU_2842 | DVU_1515 | DVU_2842 | DVU_1515 | Type II DNA modification methyltransferase, putative; Identified by similarity to SP:P11876; match to protein family HMM PF00145; match to protein family HMM TIGR00675. | Type II DNA modification methyltransferase, putative; Identified by match to protein family HMM PF00145; match to protein family HMM TIGR00675. | 0.929 |
DVU_2842 | DVU_1746 | DVU_2842 | DVU_1746 | Type II DNA modification methyltransferase, putative; Identified by similarity to SP:P11876; match to protein family HMM PF00145; match to protein family HMM TIGR00675. | C-5 cytosine-specific DNA methylase family protein; Identified by match to protein family HMM PF00145; match to protein family HMM TIGR00675; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.930 |
DVU_2842 | ahcY | DVU_2842 | DVU_0607 | Type II DNA modification methyltransferase, putative; Identified by similarity to SP:P11876; match to protein family HMM PF00145; match to protein family HMM TIGR00675. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.905 |
DVU_2842 | metK | DVU_2842 | DVU_2449 | Type II DNA modification methyltransferase, putative; Identified by similarity to SP:P11876; match to protein family HMM PF00145; match to protein family HMM TIGR00675. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.917 |
ahcY | DVU_1515 | DVU_0607 | DVU_1515 | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | Type II DNA modification methyltransferase, putative; Identified by match to protein family HMM PF00145; match to protein family HMM TIGR00675. | 0.905 |
ahcY | DVU_1585 | DVU_0607 | DVU_1585 | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | Vitamin B12-dependent methionine synthase family protein; Identified by similarity to SP:P37586; match to protein family HMM PF00809; match to protein family HMM PF02310; match to protein family HMM PF02574; match to protein family HMM PF02607. | 0.960 |