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bioB protein (Desulfovibrio vulgaris Hildenborough) - STRING interaction network
"bioB" - Biotin synthase in Desulfovibrio vulgaris Hildenborough
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family (310 aa)    
Predicted Functional Partners:
bioA
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily (542 aa)
   
  0.998
bioD
ATP-dependent dethiobiotin synthetase BioD; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (246 aa)
 
 
  0.998
birA
Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor (330 aa)
 
 
  0.991
bioF
8-amino-7-oxononanoate synthase; Identified by similarity to SP-P22806 (424 aa)
   
  0.958
DVU_1835
Biotin--acetyl-CoA-carboxylase ligase; Identified by match to protein family HMM PF03099; match to protein family HMM TIGR00121 (304 aa)
   
 
  0.910
DVU_2560
Conserved domain protein; Identified by similarity to SP-O84537 (128 aa)
   
   
  0.865
DVU_2561
Oxidoreductase, short chain dehydrogenase/reductase family; Identified by match to protein family HMM PF00106 (342 aa)
   
   
  0.862
thiG
Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (265 aa)
 
 
  0.850
DVU_1767
Radical SAM domain protein; Identified by match to protein family HMM PF04055 (322 aa)
   
   
 
0.813
thiC
Thiamine biosynthesis protein ThiC; Identified by match to protein family HMM PF01964; match to protein family HMM TIGR00190 (429 aa)
 
   
  0.761
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris Hildenborough, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
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