Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DVU_2841Type II restriction endonuclease, putative; Identified by similarity to SP:P14633. (399 aa)    
Predicted Functional Partners:
DVU_2842
Type II DNA modification methyltransferase, putative; Identified by similarity to SP:P11876; match to protein family HMM PF00145; match to protein family HMM TIGR00675.
 
  
 0.902
DVU_2843
DNA mismatch endonuclease Vsr, putative; May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.
    0.892
DVU_2840
Conserved hypothetical protein; Identified by similarity to OMNI:VCA0483.
       0.773
DVU_1515
Type II DNA modification methyltransferase, putative; Identified by match to protein family HMM PF00145; match to protein family HMM TIGR00675.
 
  
 0.731
DVU_1746
C-5 cytosine-specific DNA methylase family protein; Identified by match to protein family HMM PF00145; match to protein family HMM TIGR00675; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
 
   
 0.686
mutL
DNA mismatch repair protein MutL, putative; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
   
 
 0.573
DVU_2844
Hypothetical protein; Identified by Glimmer2; putative.
  
    0.520
DVU_2845
HIT family protein; Identified by similarity to SP:O07513; match to protein family HMM PF01230.
  
    0.510
DVU_2846
Hypothetical protein; Identified by Glimmer2; putative.
  
    0.501
DVU_2034
Hypothetical protein; Identified by Glimmer2; putative.
    
   0.415
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
Server load: low (18%) [HD]