folC protein (Desulfovibrio vulgaris Hildenborough)

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Your Current Organism:

Desulfovibrio vulgaris Hildenborough

NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
folC	folK	DVU_2882	DVU_1656	Folylpolyglutamate synthase; Identified by similarity to SP:P15925; match to protein family HMM TIGR01499.	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Identified by similarity to SP:P26281; match to protein family HMM PF01288; match to protein family HMM TIGR01498.	0.778
folC	folP	DVU_2882	DVU_1279	Folylpolyglutamate synthase; Identified by similarity to SP:P15925; match to protein family HMM TIGR01499.	Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.	0.999
folC	gcvPB	DVU_2882	DVU_1424	Folylpolyglutamate synthase; Identified by similarity to SP:P15925; match to protein family HMM TIGR01499.	Glycine cleavage system P protein, subunit 2; Identified by similarity to SP:P54377; Belongs to the GcvP family.	0.626
folC	glgA	DVU_2882	DVU_2244	Folylpolyglutamate synthase; Identified by similarity to SP:P15925; match to protein family HMM TIGR01499.	Glycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose.	0.641
folC	glyA	DVU_2882	DVU_1203	Folylpolyglutamate synthase; Identified by similarity to SP:P15925; match to protein family HMM TIGR01499.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism; Belongs to the SHMT family.	0.688
folC	guaA	DVU_2882	DVU_1043	Folylpolyglutamate synthase; Identified by similarity to SP:P15925; match to protein family HMM TIGR01499.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.662
folC	ispD	DVU_2882	DVU_1454	Folylpolyglutamate synthase; Identified by similarity to SP:P15925; match to protein family HMM TIGR01499.	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF); In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.	0.617
folC	ribD	DVU_2882	DVU_1201	Folylpolyglutamate synthase; Identified by similarity to SP:P15925; match to protein family HMM TIGR01499.	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.	0.608
folC	ribF	DVU_2882	DVU_0450	Folylpolyglutamate synthase; Identified by similarity to SP:P15925; match to protein family HMM TIGR01499.	Riboflavin biosynthesis protein RibF; Identified by similarity to SP:P08391; match to protein family HMM PF01687; match to protein family HMM TIGR00083; Belongs to the ribF family.	0.608
folC	thiD	DVU_2882	DVU_0931	Folylpolyglutamate synthase; Identified by similarity to SP:P15925; match to protein family HMM TIGR01499.	Phosphomethylpyrimidine kinase; Identified by match to protein family HMM TIGR00097.	0.648
folK	folC	DVU_1656	DVU_2882	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Identified by similarity to SP:P26281; match to protein family HMM PF01288; match to protein family HMM TIGR01498.	Folylpolyglutamate synthase; Identified by similarity to SP:P15925; match to protein family HMM TIGR01499.	0.778
folK	folP	DVU_1656	DVU_1279	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Identified by similarity to SP:P26281; match to protein family HMM PF01288; match to protein family HMM TIGR01498.	Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.	0.999
folK	ispD	DVU_1656	DVU_1454	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Identified by similarity to SP:P26281; match to protein family HMM PF01288; match to protein family HMM TIGR01498.	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF); In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.	0.581
folK	ribD	DVU_1656	DVU_1201	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Identified by similarity to SP:P26281; match to protein family HMM PF01288; match to protein family HMM TIGR01498.	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.	0.714
folP	folC	DVU_1279	DVU_2882	Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.	Folylpolyglutamate synthase; Identified by similarity to SP:P15925; match to protein family HMM TIGR01499.	0.999
folP	folK	DVU_1279	DVU_1656	Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Identified by similarity to SP:P26281; match to protein family HMM PF01288; match to protein family HMM TIGR01498.	0.999
folP	gcvPB	DVU_1279	DVU_1424	Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.	Glycine cleavage system P protein, subunit 2; Identified by similarity to SP:P54377; Belongs to the GcvP family.	0.603
folP	glgA	DVU_1279	DVU_2244	Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.	Glycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose.	0.613
folP	ribD	DVU_1279	DVU_1201	Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.	0.630
folP	thiD	DVU_1279	DVU_0931	Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.	Phosphomethylpyrimidine kinase; Identified by match to protein family HMM TIGR00097.	0.690

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