Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DVU_2973Integration host factor, beta subunit; Identified by similarity to SP:Q06607; match to protein family HMM PF00216. (91 aa)    
Predicted Functional Partners:
hup-1
DNA-binding protein HU; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
 
 
 0.998
hupB
DNA-binding protein HU, beta subunit; Identified by similarity to SP:P02346; match to protein family HMM PF00216; Belongs to the bacterial histone-like protein family.
 
  
 0.887
hup-4
DNA-binding protein HU; Identified by similarity to SP:P02341; similar to SP:P08821; similar to GP:14028719; match to protein family HMM PF00216; Belongs to the bacterial histone-like protein family.
 
  
 0.855
DVU_2106
Sigma-54 dependent transcriptional regulator; Identified by match to protein family HMM PF00158; match to protein family HMM PF00785; match to protein family HMM PF00989; match to protein family HMM TIGR00229; match to protein family HMM TIGR01199.
   
  
 0.688
cheD
Chemotaxis protein CheD, putative; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
  
    0.676
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
   
 
 0.659
rplS
Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
  
   0.633
hup-3
DNA-binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions; Belongs to the bacterial histone-like protein family.
 
 
0.615
csrA
Carbon storage regulator; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
  
 
 0.564
DVU_2975
Hydrolase, putative; Identified by match to protein family HMM PF04307.
  
    0.558
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
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