STRINGSTRING
kdsB protein (Desulfovibrio vulgaris Hildenborough) - STRING interaction network
"kdsB" - 3-deoxy-manno-octulosonate cytidylyltransferase in Desulfovibrio vulgaris Hildenborough
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kdsB3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (252 aa)    
Predicted Functional Partners:
DVU_1625
Phosphatase, YrbI family; Identified by match to protein family HMM TIGR01662; match to protein family HMM TIGR01670 (175 aa)
  0.986
DVU_0335
3-deoxy-D-manno-octulosonic-acid transferase, putative; Identified by similarity to GP-17221411 (530 aa)
 
 
  0.981
DVU_0160
Carbohydrate isomerase, KpsF/GutQ family; Identified by match to protein family HMM PF00571; match to protein family HMM PF01380; match to protein family HMM TIGR00393; Belongs to the SIS family. GutQ/KpsF subfamily (331 aa)
 
   
  0.917
kdsA
2-dehydro-3-deoxyphosphooctonate aldolase; Identified by match to protein family HMM PF00793; match to protein family HMM TIGR01362; Belongs to the KdsA family (273 aa)
 
 
  0.887
carA
Carbamoyl-phosphate synthase small chain; Identified by similarity to SP-P25993; match to protein family HMM PF00117; match to protein family HMM PF00988; match to protein family HMM TIGR01368 (375 aa)
              0.886
lpxK
Tetraacyldisaccharide 4’-kinase; Transfers the gamma-phosphate of ATP to the 4’-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4’-bis-phosphate (lipid IVA) (354 aa)
   
  0.863
DVU_0341
3-deoxy-D-manno-octulosonate cytidylyltransferase; Identified by similarity to SP-P42216; match to protein family HMM PF02348 (256 aa)
   
   
 
0.826
lpxC
UDP-3-O-acyl-N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family (308 aa)
 
 
  0.821
lpxA
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (267 aa)
 
   
  0.821
lpxB
Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (376 aa)
 
   
  0.817
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris Hildenborough, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
Server load: low (17%) [HD]