STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemLGlutamate-1-semialdehyde-2,1-aminomutase; Identified by similarity to SP:P30949; match to protein family HMM PF00202; match to protein family HMM TIGR00713; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. (423 aa)    
Predicted Functional Partners:
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.997
hemB
Porphobilinogen synthase; Identified by match to protein family HMM PF00490; Belongs to the ALAD family.
 
 
 0.994
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.973
spsF
Spore coat polysaccharide biosynthesis protein spsF; Identified by match to protein family HMM PF02348.
      0.885
DVU_0734
Uroporphyrinogen III synthase/methyltransferase; Identified by similarity to GP:12655814; match to protein family HMM PF00590; match to protein family HMM PF02602; match to protein family HMM TIGR01369; match to protein family HMM TIGR01469.
 
  
 0.874
DVU_1463
Siroheme synthase, N-terminal domain protein; Identified by match to protein family HMM TIGR01470.
   
 0.847
fabD
Malonyl CoA-acyl carrier protein transacylase; Identified by match to protein family HMM PF00698; match to protein family HMM TIGR00128.
 
  
 0.734
DVU_0867
Aromatic amino acid decarboxylase, putative; Identified by similarity to GP:6900962; match to protein family HMM PF00282.
 
 
    0.732
DVU_3167
Heme biosynthesis protein, putative; Identified by similarity to SP:Q52522.
  
  
 0.661
DVU_3006
Polysaccharide biosynthesis protein/methyltransferase, putative; Identified by similarity to SP:P39626; similar to GP:10179847; match to protein family HMM PF02348.
      0.622
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
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