Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rbODesulfoferrodoxin; Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity; Belongs to the desulfoferrodoxin family. (126 aa)    
Predicted Functional Partners:
rub
Rubredoxin; Rubredoxin is a small nonheme, iron protein lacking acid- labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.
  
  
 0.992
roO
Rubredoxin-oxygen oxidoreductase; Identified by similarity to SP:Q9F0J6; match to protein family HMM PF00258; match to protein family HMM PF00753.
  
 0.954
rr
Rubrerythrin; May provide oxidative stress protection via catalytic reduction of intracellular hydrogen peroxide.
 
  
 0.872
DVU_1568
Ferritin; Iron-storage protein.
  
  
 0.871
DVU_1422
Identified by match to protein family HMM PF00691.
   
    0.841
sodB
Superoxide dismutase, Fe; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.813
dcrA
Methyl-accepting chemotaxis protein DcrA; Identified by similarity to SP:P35841; match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF00785; match to protein family HMM TIGR00229.
     
 0.800
rdl
Identified by match to protein family HMM PF00301; Belongs to the rubredoxin family.
  
  
 0.775
hup-4
DNA-binding protein HU; Identified by similarity to SP:P02341; similar to SP:P08821; similar to GP:14028719; match to protein family HMM PF00216; Belongs to the bacterial histone-like protein family.
   
    0.748
DVU_0665
Nitrogen fixation protein nifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins; Belongs to the NifU family.
  
  
 0.723
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
Server load: low (14%) [HD]