STRINGSTRING
purA protein (Desulfovibrio vulgaris Hildenborough) - STRING interaction network
"purA" - Adenylosuccinate synthetase in Desulfovibrio vulgaris Hildenborough
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family (426 aa)    
Predicted Functional Partners:
purB
Adenylosuccinate lyase; Identified by similarity to SP-P12047; match to protein family HMM PF00206; match to protein family HMM TIGR00928; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily (430 aa)
 
 
  0.990
guaB
Inosine-5’-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5’-phosphate (IMP) to xanthosine 5’-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (485 aa)
 
 
  0.986
DVU_3206
Phosphoribosylaminoimidazolecarboxamide formyltransferase, putative; Identified by similarity to SP-P12048; match to protein family HMM PF01808 (510 aa)
 
  0.977
DVU_3235
IMP cyclohydrolase, putative; Identified by similarity to SP-P12048; match to protein family HMM PF02142 (200 aa)
 
  0.968
hpt
Hypoxanthine phosphoribosyltransferase; Identified by similarity to SP-P37472; match to protein family HMM PF00156; match to protein family HMM TIGR01203; Belongs to the purine/pyrimidine phosphoribosyltransferase family (176 aa)
   
 
  0.963
pyrB
Aspartate carbamoyltransferase; Identified by similarity to SP-P05654; match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00670 (317 aa)
 
 
  0.960
argG
Argininosuccinate synthase; Identified by similarity to GP-20150951; match to protein family HMM PF00764; match to protein family HMM TIGR00032; Belongs to the argininosuccinate synthase family. Type 1 subfamily (396 aa)
   
 
  0.956
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP (515 aa)
 
   
  0.937
DVU_3014
Asparagine synthetase, glutamine-hydrolyzing; Identified by match to protein family HMM PF00310; match to protein family HMM PF00733; match to protein family HMM TIGR01536 (697 aa)
   
 
  0.917
nadB
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate (528 aa)
         
  0.913
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris Hildenborough, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
Server load: low (16%) [HD]