node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DVU_0319 | DVU_3176 | DVU_0319 | DVU_3176 | Udp-n-acetylglucosamine/udp-n-acetylgalactosamine 4-epimerase; Identified by similarity to GP:20560072; match to protein family HMM PF01370 | Udp-n-acetyl-d-glucosamine/udp-n-acetyl-d-galactosamine dehydrogenase; Identified by similarity to SP:P39861; match to protein family HMM PF00984; match to protein family HMM PF03720; match to protein family HMM PF03721 | 0.995 |
DVU_0319 | glmU | DVU_0319 | DVU_2668 | Udp-n-acetylglucosamine/udp-n-acetylgalactosamine 4-epimerase; Identified by similarity to GP:20560072; match to protein family HMM PF01370 | Bifunctional n-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain | 0.908 |
DVU_0319 | lpxA | DVU_0319 | DVU_2367 | Udp-n-acetylglucosamine/udp-n-acetylgalactosamine 4-epimerase; Identified by similarity to GP:20560072; match to protein family HMM PF01370 | Acyl-(acyl-carrier-protein)--udp-n- acetylglucosamine o-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell | 0.809 |
DVU_0319 | murA | DVU_0319 | DVU_3258 | Udp-n-acetylglucosamine/udp-n-acetylgalactosamine 4-epimerase; Identified by similarity to GP:20560072; match to protein family HMM PF01370 | Udp-n-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine | 0.908 |
DVU_2505 | DVU_2510 | DVU_2505 | DVU_2510 | Cell cycle protein, ftsw/roda/spove family; Belongs to the SEDS family | Cell division protein ftsi (penicillin-binding protein 3); Penicillin-binding protein; Identified by similarity to SP:P11882; match to protein family HMM PF00905; match to protein family HMM PF03717 | 0.995 |
DVU_2505 | glmU | DVU_2505 | DVU_2668 | Cell cycle protein, ftsw/roda/spove family; Belongs to the SEDS family | Bifunctional n-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain | 0.514 |
DVU_2505 | mraY | DVU_2505 | DVU_2507 | Cell cycle protein, ftsw/roda/spove family; Belongs to the SEDS family | Phospho-n-acetylmuramoyl-pentapeptide-transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan | 0.987 |
DVU_2505 | murA | DVU_2505 | DVU_3258 | Cell cycle protein, ftsw/roda/spove family; Belongs to the SEDS family | Udp-n-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine | 0.845 |
DVU_2505 | murB | DVU_2505 | DVU_2502 | Cell cycle protein, ftsw/roda/spove family; Belongs to the SEDS family | Udp-n-acetylenolpyruvoylglucosamine reductase; Cell wall formation | 0.966 |
DVU_2505 | murC | DVU_2505 | DVU_2503 | Cell cycle protein, ftsw/roda/spove family; Belongs to the SEDS family | Udp-n-acetylmuramate--l-alanine ligase; Cell wall formation | 0.986 |
DVU_2505 | murD | DVU_2505 | DVU_2506 | Cell cycle protein, ftsw/roda/spove family; Belongs to the SEDS family | Udp-n-acetylmuramoylalanine--d-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) | 0.984 |
DVU_2510 | DVU_2505 | DVU_2510 | DVU_2505 | Cell division protein ftsi (penicillin-binding protein 3); Penicillin-binding protein; Identified by similarity to SP:P11882; match to protein family HMM PF00905; match to protein family HMM PF03717 | Cell cycle protein, ftsw/roda/spove family; Belongs to the SEDS family | 0.995 |
DVU_2510 | glmU | DVU_2510 | DVU_2668 | Cell division protein ftsi (penicillin-binding protein 3); Penicillin-binding protein; Identified by similarity to SP:P11882; match to protein family HMM PF00905; match to protein family HMM PF03717 | Bifunctional n-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain | 0.470 |
DVU_2510 | mraY | DVU_2510 | DVU_2507 | Cell division protein ftsi (penicillin-binding protein 3); Penicillin-binding protein; Identified by similarity to SP:P11882; match to protein family HMM PF00905; match to protein family HMM PF03717 | Phospho-n-acetylmuramoyl-pentapeptide-transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan | 0.964 |
DVU_2510 | murA | DVU_2510 | DVU_3258 | Cell division protein ftsi (penicillin-binding protein 3); Penicillin-binding protein; Identified by similarity to SP:P11882; match to protein family HMM PF00905; match to protein family HMM PF03717 | Udp-n-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine | 0.845 |
DVU_2510 | murB | DVU_2510 | DVU_2502 | Cell division protein ftsi (penicillin-binding protein 3); Penicillin-binding protein; Identified by similarity to SP:P11882; match to protein family HMM PF00905; match to protein family HMM PF03717 | Udp-n-acetylenolpyruvoylglucosamine reductase; Cell wall formation | 0.919 |
DVU_2510 | murC | DVU_2510 | DVU_2503 | Cell division protein ftsi (penicillin-binding protein 3); Penicillin-binding protein; Identified by similarity to SP:P11882; match to protein family HMM PF00905; match to protein family HMM PF03717 | Udp-n-acetylmuramate--l-alanine ligase; Cell wall formation | 0.976 |
DVU_2510 | murD | DVU_2510 | DVU_2506 | Cell division protein ftsi (penicillin-binding protein 3); Penicillin-binding protein; Identified by similarity to SP:P11882; match to protein family HMM PF00905; match to protein family HMM PF03717 | Udp-n-acetylmuramoylalanine--d-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) | 0.975 |
DVU_3176 | DVU_0319 | DVU_3176 | DVU_0319 | Udp-n-acetyl-d-glucosamine/udp-n-acetyl-d-galactosamine dehydrogenase; Identified by similarity to SP:P39861; match to protein family HMM PF00984; match to protein family HMM PF03720; match to protein family HMM PF03721 | Udp-n-acetylglucosamine/udp-n-acetylgalactosamine 4-epimerase; Identified by similarity to GP:20560072; match to protein family HMM PF01370 | 0.995 |
DVU_3176 | glmU | DVU_3176 | DVU_2668 | Udp-n-acetyl-d-glucosamine/udp-n-acetyl-d-galactosamine dehydrogenase; Identified by similarity to SP:P39861; match to protein family HMM PF00984; match to protein family HMM PF03720; match to protein family HMM PF03721 | Bifunctional n-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain | 0.906 |