Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
frdBFumarate reductase, iron-sulfur protein; Identified by similarity to SP:P17596; match to protein family HMM PF00037; match to protein family HMM TIGR00384. (247 aa)    
Predicted Functional Partners:
sucCD
succinyl-CoA synthase, beta/alpha subunits; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 0.999
frdC
Fumarate reductase, cytochrome b subunit; Identified by similarity to SP:P17413.
 
 0.999
fdrA
Fumarate reductase, flavoprotein subunit; Identified by similarity to GP:13160058; match to protein family HMM PF00890; match to protein family HMM PF02910; match to protein family HMM TIGR01812.
 0.999
DVU_3265
Tartrate dehydratase beta subunit, putative; Identified by match to protein family HMM PF05683; match to protein family HMM TIGR00723.
  
 
 0.974
DVU_3264
Tartrate dehydratase alpha subunit, putative; Identified by similarity to SP:P05847; match to protein family HMM PF05681; match to protein family HMM TIGR00722.
  
 
 0.973
DVU_0665
Nitrogen fixation protein nifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins; Belongs to the NifU family.
  
 0.968
fumC
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.961
DVU_1772
Pyridine nucleotide-disulfide oxidoreductase; Identified by match to protein family HMM PF00070.
  
 
 0.941
DVU_3110
L-aspartate oxidase, putative; Identified by match to protein family HMM PF00890; match to protein family HMM PF02910.
 
 0.929
DVU_2674
Succinate dehydrogenase and fumarate reductase iron-sulfur protein; Identified by match to protein family HMM PF00037; match to protein family HMM PF00111; match to protein family HMM TIGR00384; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
  
 
0.925
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
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