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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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experimentally determined
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DVU_3293Thiamine pyrophosphate-requiring enzyme; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family. (547 aa)    
Predicted Functional Partners:
ilvN-2
Acetolactate synthase, small subunit; Identified by similarity to SP:P00894; match to protein family HMM PF01842; match to protein family HMM TIGR00119.
 
 0.986
DVU_0361
Acetolactate synthase III, small subunit, putative; Identified by match to protein family HMM PF01842.
 0.985
ilvN-1
Acetolactate synthase, small subunit; Identified by similarity to SP:P37252; match to protein family HMM PF01842; match to protein family HMM TIGR00119.
  
 0.984
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
  
 
 0.971
poR
Pyruvate-ferredoxin oxidoreductase; Identified by similarity to GP:1770208; match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855.
  
 
 0.961
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
  
 0.957
ilvB-1
Acetolactate synthase, large subunit, biosynthetic type; Identified by similarity to SP:P08142; match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR00118.
  
  
 
0.921
ilvB-2
Acetolactate synthase, large subunit, biosynthetic type; Identified by similarity to SP:P00893; match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR00118.
  
  
 
0.921
DVU_3294
Aldehyde dehydrogenase (NADP) family protein; Identified by match to protein family HMM PF00171.
 
 0.893
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
 
 0.887
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
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