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DVU_3293 protein (Desulfovibrio vulgaris Hildenborough) - STRING interaction network
"DVU_3293" - Thiamine pyrophosphate-requiring enzyme in Desulfovibrio vulgaris Hildenborough
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second shell of interactors
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proteins of unknown 3D structure
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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DVU_3293Thiamine pyrophosphate-requiring enzyme; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family (547 aa)    
Predicted Functional Partners:
ilvC
Ketol-acid reductoisomerase (NADP(+)); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate; Belongs to the ketol-acid reductoisomerase family (331 aa)
 
 
  0.964
ilvN-2
Acetolactate synthase, small subunit; Identified by similarity to SP-P00894; match to protein family HMM PF01842; match to protein family HMM TIGR00119 (162 aa)
  0.949
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate; Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily (357 aa)
  0.946
DVU_0361
Acetolactate synthase III, small subunit, putative; Identified by match to protein family HMM PF01842 (107 aa)
   
  0.945
poR
Pyruvate synthase; Identified by similarity to GP-1770208; match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855 (1215 aa)
   
 
  0.926
ilvN-1
Acetolactate synthase, small subunit; Identified by similarity to SP-P37252; match to protein family HMM PF01842; match to protein family HMM TIGR00119 (159 aa)
 
  0.920
DVU_2147
L-serine dehydratase, putative; Identified by match to protein family HMM PF03313; match to protein family HMM PF03315 (502 aa)
     
 
    0.903
DVU_3294
Aldehyde dehydrogenase (NADP) family protein; Identified by match to protein family HMM PF00171 (464 aa)
 
   
  0.892
DVU_0414
NADP-dependent malic enzyme-related protein; Identified by match to protein family HMM PF00390; match to protein family HMM PF03949 (439 aa)
   
 
  0.847
pyk
Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family (469 aa)
   
  0.842
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris Hildenborough, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
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