STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RASGEF1BRasGEF domain family member 1B. (472 aa)    
Predicted Functional Partners:
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
    
 0.727
RASA1
RAS p21 protein activator 1.
    
 
 0.639
GRB2
Growth factor receptor bound protein 2.
     
 0.618
SOS2
SOS Ras/Rho guanine nucleotide exchange factor 2.
    
 0.608
DLL1
Delta like canonical Notch ligand 1.
      
 0.580
SHC1
SHC adaptor protein 1.
     
  0.556
SHC3
SHC adaptor protein 3.
     
  0.556
CCNK
Cyclin K.
     
  0.543
RAPGEF2
Rap guanine nucleotide exchange factor 2.
    
  0.537
RALA
RAS like proto-oncogene A.
    
 0.521
Your Current Organism:
Apteryx haastii
NCBI taxonomy Id: 8823
Other names: A. haastii, Great spotted kiwi
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.