PAX6 protein (Apteryx haastii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

PAX6

Paired box 6. (436 aa)

Predicted Functional Partners:

FOXJ2

0.922

ENSAHAP00000010047

0.879

ENSAHAP00000024578

0.869

SP3

0.867

TBR1

0.856

MYB

0.842

IPO13

0.839

TIMM9

0.829

CUX1

0.823

ENSAHAP00000007737

0.808

Your Current Organism:

Apteryx haastii

NCBI taxonomy Id: 8823
Other names: A. haastii, Great spotted kiwi

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUX1	PAX6	ENSAHAP00000008854	ENSAHAP00000001410	Cut like homeobox 1.	Paired box 6.	0.823
CUX1	TBR1	ENSAHAP00000008854	ENSAHAP00000016950	Cut like homeobox 1.	T-box brain transcription factor 1.	0.821
ENSAHAP00000007737	PAX6	ENSAHAP00000007737	ENSAHAP00000001410	annotation not available	Paired box 6.	0.808
ENSAHAP00000007737	TIMM9	ENSAHAP00000007737	ENSAHAP00000024430	annotation not available	Translocase of inner mitochondrial membrane 9.	0.976
ENSAHAP00000010047	ENSAHAP00000024578	ENSAHAP00000010047	ENSAHAP00000024578	annotation not available	annotation not available	0.529
ENSAHAP00000010047	PAX6	ENSAHAP00000010047	ENSAHAP00000001410	annotation not available	Paired box 6.	0.879
ENSAHAP00000010047	TBR1	ENSAHAP00000010047	ENSAHAP00000016950	annotation not available	T-box brain transcription factor 1.	0.506
ENSAHAP00000024578	ENSAHAP00000010047	ENSAHAP00000024578	ENSAHAP00000010047	annotation not available	annotation not available	0.529
ENSAHAP00000024578	PAX6	ENSAHAP00000024578	ENSAHAP00000001410	annotation not available	Paired box 6.	0.869
FOXJ2	MYB	ENSAHAP00000010017	ENSAHAP00000012186	Forkhead box J2.	MYB proto-oncogene, transcription factor.	0.954
FOXJ2	PAX6	ENSAHAP00000010017	ENSAHAP00000001410	Forkhead box J2.	Paired box 6.	0.922
IPO13	PAX6	ENSAHAP00000020678	ENSAHAP00000001410	Importin 13.	Paired box 6.	0.839
MYB	FOXJ2	ENSAHAP00000012186	ENSAHAP00000010017	MYB proto-oncogene, transcription factor.	Forkhead box J2.	0.954
MYB	PAX6	ENSAHAP00000012186	ENSAHAP00000001410	MYB proto-oncogene, transcription factor.	Paired box 6.	0.842
PAX6	CUX1	ENSAHAP00000001410	ENSAHAP00000008854	Paired box 6.	Cut like homeobox 1.	0.823
PAX6	ENSAHAP00000007737	ENSAHAP00000001410	ENSAHAP00000007737	Paired box 6.	annotation not available	0.808
PAX6	ENSAHAP00000010047	ENSAHAP00000001410	ENSAHAP00000010047	Paired box 6.	annotation not available	0.879
PAX6	ENSAHAP00000024578	ENSAHAP00000001410	ENSAHAP00000024578	Paired box 6.	annotation not available	0.869
PAX6	FOXJ2	ENSAHAP00000001410	ENSAHAP00000010017	Paired box 6.	Forkhead box J2.	0.922
PAX6	IPO13	ENSAHAP00000001410	ENSAHAP00000020678	Paired box 6.	Importin 13.	0.839