CNN2 protein (Apteryx haastii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

CNN2

Calponin 2. (420 aa)

Predicted Functional Partners:

ASPM

0.923

ENSAHAP00000010783

0.804

WDR90

0.794

FSCN2

0.793

NME8

0.792

CALB2

0.779

CALML4

0.728

PLS1

0.725

MYOCD

0.711

ENSAHAP00000010864

0.710

Your Current Organism:

Apteryx haastii

NCBI taxonomy Id: 8823
Other names: A. haastii, Great spotted kiwi

Export your current network:

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same PNG format, but at higher resolution

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASPM	CNN2	ENSAHAP00000022768	ENSAHAP00000001434	Abnormal spindle microtubule assembly.	Calponin 2.	0.923
CALB2	CNN2	ENSAHAP00000026511	ENSAHAP00000001434	Calbindin 2.	Calponin 2.	0.779
CALB2	ENSAHAP00000010864	ENSAHAP00000026511	ENSAHAP00000010864	Calbindin 2.	annotation not available	0.511
CALB2	NME8	ENSAHAP00000026511	ENSAHAP00000002942	Calbindin 2.	NME/NM23 family member 8.	0.559
CALB2	WDR90	ENSAHAP00000026511	ENSAHAP00000026577	Calbindin 2.	WD repeat domain 90.	0.632
CALML4	CNN2	ENSAHAP00000028045	ENSAHAP00000001434	Calmodulin like 4.	Calponin 2.	0.728
CALML4	ENSAHAP00000010864	ENSAHAP00000028045	ENSAHAP00000010864	Calmodulin like 4.	annotation not available	0.511
CALML4	NME8	ENSAHAP00000028045	ENSAHAP00000002942	Calmodulin like 4.	NME/NM23 family member 8.	0.559
CALML4	WDR90	ENSAHAP00000028045	ENSAHAP00000026577	Calmodulin like 4.	WD repeat domain 90.	0.632
CNN2	ASPM	ENSAHAP00000001434	ENSAHAP00000022768	Calponin 2.	Abnormal spindle microtubule assembly.	0.923
CNN2	CALB2	ENSAHAP00000001434	ENSAHAP00000026511	Calponin 2.	Calbindin 2.	0.779
CNN2	CALML4	ENSAHAP00000001434	ENSAHAP00000028045	Calponin 2.	Calmodulin like 4.	0.728
CNN2	ENSAHAP00000010783	ENSAHAP00000001434	ENSAHAP00000010783	Calponin 2.	annotation not available	0.804
CNN2	ENSAHAP00000010864	ENSAHAP00000001434	ENSAHAP00000010864	Calponin 2.	annotation not available	0.710
CNN2	FSCN2	ENSAHAP00000001434	ENSAHAP00000026688	Calponin 2.	Fascin actin-bundling protein 2, retinal.	0.793
CNN2	MYOCD	ENSAHAP00000001434	ENSAHAP00000025566	Calponin 2.	Myocardin.	0.711
CNN2	NME8	ENSAHAP00000001434	ENSAHAP00000002942	Calponin 2.	NME/NM23 family member 8.	0.792
CNN2	PLS1	ENSAHAP00000001434	ENSAHAP00000025255	Calponin 2.	Plastin 1.	0.725
CNN2	WDR90	ENSAHAP00000001434	ENSAHAP00000026577	Calponin 2.	WD repeat domain 90.	0.794
ENSAHAP00000010783	CNN2	ENSAHAP00000010783	ENSAHAP00000001434	annotation not available	Calponin 2.	0.804