STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TWNKTwinkle mtDNA helicase. (669 aa)    
Predicted Functional Partners:
POLG
DNA polymerase gamma, catalytic subunit.
   
 
 0.957
POLG2
DNA polymerase gamma 2, accessory subunit.
     
 0.935
ENSAHAP00000002402
annotation not available
    
   0.925
NUBPL
Nucleotide binding protein like.
    
 
 0.913
POLRMT
RNA polymerase mitochondrial.
   
 
 0.889
PTGES2
Prostaglandin E synthase 2.
    
   0.880
TFAM
Transcription factor A, mitochondrial.
     
 0.826
GALM
Galactose mutarotase.
     
  0.818
GALT
Galactose-1-phosphate uridylyltransferase.
     
  0.818
PDIA3
Protein disulfide isomerase family A member 3.
    
   0.792
Your Current Organism:
Apteryx haastii
NCBI taxonomy Id: 8823
Other names: A. haastii, Great spotted kiwi
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.