Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PTPN21Protein tyrosine phosphatase non-receptor type 21. (1151 aa)    
Predicted Functional Partners:
RHPN1
Rhophilin Rho GTPase binding protein 1.
    
 
 0.910
PARD6G
Par-6 family cell polarity regulator gamma.
    
 
 0.828
PARD6B
Par-6 family cell polarity regulator beta.
    
 
 0.828
BAG3
BCL2 associated athanogene 3.
   
  0.737
RHPN2
Rhophilin Rho GTPase binding protein 2.
    
 
 0.727
PTS
6-pyruvoyltetrahydropterin synthase.
    
 
 0.724
YAP1
Yes associated protein 1.
   
 0.688
WWTR1
WW domain containing transcription regulator 1.
   
 0.688
KCTD18
Potassium channel tetramerization domain containing 18.
      
 0.663
HOOK3
Hook microtubule tethering protein 3.
    
 0.658
Your Current Organism:
Apteryx haastii
NCBI taxonomy Id: 8823
Other names: A. haastii, Great spotted kiwi
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.