Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKT3AKT serine/threonine kinase 3. (479 aa)    
Predicted Functional Partners:
PDPK1
3-phosphoinositide dependent protein kinase 1.
   
 0.983
MTOR
Mechanistic target of rapamycin kinase.
    
 0.983
PIK3CA
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha.
   
 0.980
ILK
Integrin linked kinase.
   
 0.977
GSK3B
Glycogen synthase kinase 3 beta.
   
 0.976
MDM2
MDM2 proto-oncogene.
    
 0.976
TSC1
TSC complex subunit 1.
    
 0.974
TSC2
TSC complex subunit 2.
    
 0.974
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
   
 0.973
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
   
 0.971
Your Current Organism:
Apteryx haastii
NCBI taxonomy Id: 8823
Other names: A. haastii, Great spotted kiwi
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