STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TYK2Tyrosine kinase 2. (1186 aa)    
Predicted Functional Partners:
STAT3
Signal transducer and activator of transcription 3.
   
 0.992
IFNAR1
Interferon alpha and beta receptor subunit 1.
   
 0.992
SOCS1
Suppressor of cytokine signaling 1.
    
 0.983
IL6ST
Interleukin 6 signal transducer.
    
 0.981
ENSAHAP00000027046
annotation not available
   
 0.981
SOCS3
Suppressor of cytokine signaling 3.
   
 0.979
ENSAHAP00000017114
annotation not available
    
 0.965
IFNGR2
Interferon gamma receptor 2.
    
 0.962
STAT4
Signal transducer and activator of transcription 4.
   
 0.959
IL10RA
Interleukin 10 receptor subunit alpha.
    
 0.958
Your Current Organism:
Apteryx haastii
NCBI taxonomy Id: 8823
Other names: A. haastii, Great spotted kiwi
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.