Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MAP4K5Mitogen-activated protein kinase kinase kinase kinase 5. (819 aa)    
Predicted Functional Partners:
MAP3K1
Mitogen-activated protein kinase kinase kinase 1.
   
 0.909
TRAF1
TNF receptor associated factor 1.
    
  0.823
TRAF2
TNF receptor associated factor 2.
    
  0.823
ENSAHAP00000025952
annotation not available
    
 0.814
MAPK8IP1
Mitogen-activated protein kinase 8 interacting protein 1.
    
 0.791
ENSAHAP00000010541
annotation not available
    
 0.791
CRKL
CRK like proto-oncogene, adaptor protein.
    
 
 0.745
GRB2
Growth factor receptor bound protein 2.
    
 
 0.734
CRK
CRK proto-oncogene, adaptor protein.
    
 
 0.726
GRAP2
GRB2 related adaptor protein 2.
   
 
 0.724
Your Current Organism:
Apteryx haastii
NCBI taxonomy Id: 8823
Other names: A. haastii, Great spotted kiwi
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