STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thrBHomoserine kinase (EC 2.7.1.39); COG: Putative homoserine kinase type II (protein kinase fold); Pfam: Phosphotransferase enzyme family::PF01636; Belongs to the pseudomonas-type ThrB family. (322 aa)    
Predicted Functional Partners:
CBW74929.1
Threonine synthase (EC 4.2.3.1); COG: Threonine synthase; Pfam: Pyridoxal-phosphate dependent enzyme::PF00291.
    
 0.915
CBW74928.1
Homoserine dehydrogenase (EC 1.1.1.3); COG: Homoserine dehydrogenase; Pfam: ACT domain::PF01842<br>Homoserine dehydrogenase::PF00742<br>Homoserine dehydrogenase, NAD binding domain::PF03447.
    
 0.908
CBW74899.1
Cystathionine beta-lyase (EC 4.4.1.8); COG: Cystathionine beta-lyases/cystathionine gamma-synthases; Pfam: Cys/Met metabolism PLP-dependent enzyme::PF01053.
  
  
  0.830
ilvE
Branched-chain amino acid aminotransferase (EC 2.6.1.42); Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
     
 0.804
metE
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (EC 2.1.1.14); Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
     
  0.800
metZ
O-acetylhomoserine sulfhydrolase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
     
  0.800
CBW73683.1
L-serine dehydratase (EC 4.3.1.17); COG: L-serine deaminase; Pfam: Serine dehydratase alpha chain::PF03313<br>Serine dehydratase beta chain::PF03315; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
  0.800
CBW76224.1
5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) cobalamin-binding subunit; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
  0.800
CBW76223.1
5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) homocysteine-binding subunit; COG: Methionine synthase I (cobalamin-dependent), methyltransferase domain; Pfam: Homocysteine S-methyltransferase::PF02574.
     
  0.800
ahcY
Adenosylhomocysteinase (EC 3.3.1.1); May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
     
  0.800
Your Current Organism:
Paraburkholderia rhizoxinica
NCBI taxonomy Id: 882378
Other names: Burkholderia rhizoxinica HKI 454, P. rhizoxinica HKI 454, Paraburkholderia rhizoxinica HKI 454
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