STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aspSAspartyl-tRNA synthetase (EC 6.1.1.12); Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (626 aa)    
Predicted Functional Partners:
gatB
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B (EC 6.3.5.-); Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.
 
 
 0.987
CBW76077.1
dATP pyrophosphohydrolase (EC 3.6.1.-); COG: NTP pyrophosphohydrolases including oxidative damage repair enzymes; Pfam: NUDIX domain::PF00293.
 
   0.938
hisS
Histidyl-tRNA synthetase (EC 6.1.1.21); COG: Histidyl-tRNA synthetase; Pfam: Anticodon binding domain::PF03129<br>tRNA synthetase class II core domain (G, H, P, S and T)::PF00587.
 
  
 0.898
alaS
Alanyl-tRNA synthetase (EC 6.1.1.7); Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
 
  
 0.856
CBW75710.1
Hypothetical cytosolic protein; COG: Uncharacterized conserved protein; Pfam: Domain of unknown function DUF28::PF01709.
  
 0.819
gatC
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C (EC 6.3.5.-); Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.
  
 
 0.807
valS
Valyl-tRNA synthetase (EC 6.1.1.9); Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
  
  
 0.796
CBW76079.1
Hypothetical membrane spanning protein; COG: Uncharacterized conserved protein; Pfam: Protein of unknown function (DUF502)::PF04367.
       0.795
pheT
Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20); COG: Phenylalanyl-tRNA synthetase beta subunit; Pfam: B3/4 domain::PF03483<br>Ferredoxin-fold anticodon binding domain::PF03147<br>Putative tRNA binding domain::PF01588<br>tRNA synthetase B5 domain::PF03484.
 
  
 0.791
CBW76080.1
Hypothetical protein; COG: Uncharacterized protein conserved in bacteria; Pfam: Putative regulatory protein (CxxC_CxxC_SSSS)::PF09723.
       0.790
Your Current Organism:
Paraburkholderia rhizoxinica
NCBI taxonomy Id: 882378
Other names: Burkholderia rhizoxinica HKI 454, P. rhizoxinica HKI 454, Paraburkholderia rhizoxinica HKI 454
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