STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LRRK2Leucine rich repeat kinase 2. (2440 aa)    
Predicted Functional Partners:
DNM1L
Dynamin 1 like.
    
 0.909
EIF4EBP2
Eukaryotic translation initiation factor 4E binding protein 2.
    
 
 0.884
YWHAQ
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta.
    
  0.848
SFN
Stratifin.
    
  0.848
YWHAB
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta.
    
  0.743
YWHAE
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon.
    
  0.743
YWHAZ
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta.
    
  0.743
SNCA
Synuclein alpha.
    
 
 0.727
VPS35
VPS35 retromer complex component.
    
 
 0.721
NSF
N-ethylmaleimide sensitive factor, vesicle fusing ATPase.
    
 
 0.703
Your Current Organism:
Apteryx owenii
NCBI taxonomy Id: 8824
Other names: A. owenii, little spotted kiwi
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.