close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LRRK2Leucine rich repeat kinase 2. (2440 aa)    
Predicted Functional Partners:
LRP6
LDL receptor related protein 6.
    
 0.811
ENSAOWP00000006636
annotation not available
    
  0.799
ADGRL3
Adhesion G protein-coupled receptor L3.
    
  0.799
ENSAOWP00000019283
annotation not available
    
  0.799
ADGRL2
Adhesion G protein-coupled receptor L2.
    
  0.799
CTNNB1
Catenin beta 1.
    
 0.797
DVL1
Dishevelled segment polarity protein 1.
    
 0.750
DVL3
Dishevelled segment polarity protein 3.
    
 0.750
ENSAOWP00000010987
annotation not available
    
 0.733
NTNG1
Netrin G1.
    
 0.732
Your Current Organism:
Apteryx owenii
NCBI taxonomy Id: 8824
Other names: A. owenii, little spotted kiwi
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.