GEM protein (Apteryx owenii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

GEM

GTP binding protein overexpressed in skeletal muscle. (297 aa)

Predicted Functional Partners:

ITSN2

0.889

ENSAOWP00000016433

0.853

ITSN1

0.837

ENSAOWP00000026465

0.837

DOCK4

0.829

ENSAOWP00000000558

0.773

SHANK3

0.773

MST1R

0.762

MET

0.762

ENSAOWP00000018930

0.762

Your Current Organism:

Apteryx owenii

NCBI taxonomy Id: 8824
Other names: A. owenii, little spotted kiwi

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DOCK4	ENSAOWP00000000558	ENSAOWP00000011909	ENSAOWP00000000558	Dedicator of cytokinesis 4.	annotation not available	0.523
DOCK4	GEM	ENSAOWP00000011909	ENSAOWP00000001199	Dedicator of cytokinesis 4.	GTP binding protein overexpressed in skeletal muscle.	0.829
DOCK4	SHANK3	ENSAOWP00000011909	ENSAOWP00000007513	Dedicator of cytokinesis 4.	SH3 and multiple ankyrin repeat domains 3.	0.523
ENSAOWP00000000558	DOCK4	ENSAOWP00000000558	ENSAOWP00000011909	annotation not available	Dedicator of cytokinesis 4.	0.523
ENSAOWP00000000558	GEM	ENSAOWP00000000558	ENSAOWP00000001199	annotation not available	GTP binding protein overexpressed in skeletal muscle.	0.773
ENSAOWP00000000558	SHANK3	ENSAOWP00000000558	ENSAOWP00000007513	annotation not available	SH3 and multiple ankyrin repeat domains 3.	0.859
ENSAOWP00000016433	GEM	ENSAOWP00000016433	ENSAOWP00000001199	annotation not available	GTP binding protein overexpressed in skeletal muscle.	0.853
ENSAOWP00000018930	ENSAOWP00000026465	ENSAOWP00000018930	ENSAOWP00000026465	annotation not available	annotation not available	0.454
ENSAOWP00000018930	GEM	ENSAOWP00000018930	ENSAOWP00000001199	annotation not available	GTP binding protein overexpressed in skeletal muscle.	0.762
ENSAOWP00000018930	ITSN1	ENSAOWP00000018930	ENSAOWP00000026448	annotation not available	Intersectin 1.	0.454
ENSAOWP00000018930	ITSN2	ENSAOWP00000018930	ENSAOWP00000021434	annotation not available	Intersectin 2.	0.749
ENSAOWP00000018930	MET	ENSAOWP00000018930	ENSAOWP00000012846	annotation not available	MET proto-oncogene, receptor tyrosine kinase.	0.836
ENSAOWP00000018930	MST1R	ENSAOWP00000018930	ENSAOWP00000012051	annotation not available	Macrophage stimulating 1 receptor.	0.847
ENSAOWP00000026465	ENSAOWP00000018930	ENSAOWP00000026465	ENSAOWP00000018930	annotation not available	annotation not available	0.454
ENSAOWP00000026465	GEM	ENSAOWP00000026465	ENSAOWP00000001199	annotation not available	GTP binding protein overexpressed in skeletal muscle.	0.837
ENSAOWP00000026465	ITSN1	ENSAOWP00000026465	ENSAOWP00000026448	annotation not available	Intersectin 1.	0.965
ENSAOWP00000026465	ITSN2	ENSAOWP00000026465	ENSAOWP00000021434	annotation not available	Intersectin 2.	0.982
ENSAOWP00000026465	MET	ENSAOWP00000026465	ENSAOWP00000012846	annotation not available	MET proto-oncogene, receptor tyrosine kinase.	0.454
ENSAOWP00000026465	MST1R	ENSAOWP00000026465	ENSAOWP00000012051	annotation not available	Macrophage stimulating 1 receptor.	0.454
GEM	DOCK4	ENSAOWP00000001199	ENSAOWP00000011909	GTP binding protein overexpressed in skeletal muscle.	Dedicator of cytokinesis 4.	0.829