Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PDCD1LG2Programmed cell death 1 ligand 2. (260 aa)    
Predicted Functional Partners:
ENSAOWP00000027324
annotation not available
   
 0.999
CD274
CD274 molecule.
   
 0.985
ENSAOWP00000003706
annotation not available
   
  0.883
ENSAOWP00000016304
annotation not available
     
 0.836
CTLA4
Cytotoxic T-lymphocyte associated protein 4.
   
 
 0.724
HTR2B
5-hydroxytryptamine receptor 2B.
      
 0.700
SPOP
Speckle type BTB/POZ protein.
    
 0.695
SPOPL
Speckle type BTB/POZ protein like.
    
 0.695
CD3E
CD3e molecule.
     
 0.682
IFNG
Interferon gamma.
   
  
 0.679
Your Current Organism:
Apteryx owenii
NCBI taxonomy Id: 8824
Other names: A. owenii, little spotted kiwi
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