IGF1R protein (Apteryx owenii) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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Textmining

[Homology]

Score

IGF1R

Insulin like growth factor 1 receptor. (1364 aa)

Predicted Functional Partners:

ENSAOWP00000002065

0.936

IGF2

0.908

ENSAOWP00000020572

0.900

SHC1

0.895

PTPN1

0.894

PIK3R1

0.872

ENSAOWP00000013609

0.872

MDM2

0.867

SHC3

0.866

GRB2

0.860

Your Current Organism:

Apteryx owenii

NCBI taxonomy Id: 8824
Other names: A. owenii, little spotted kiwi

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAOWP00000002065	GRB2	ENSAOWP00000002065	ENSAOWP00000019098	annotation not available	Growth factor receptor bound protein 2.	0.692
ENSAOWP00000002065	IGF1R	ENSAOWP00000002065	ENSAOWP00000001541	annotation not available	Insulin like growth factor 1 receptor.	0.936
ENSAOWP00000002065	IGF2	ENSAOWP00000002065	ENSAOWP00000002052	annotation not available	Insulin like growth factor 2.	0.851
ENSAOWP00000002065	SHC1	ENSAOWP00000002065	ENSAOWP00000026467	annotation not available	SHC adaptor protein 1.	0.632
ENSAOWP00000002065	SHC3	ENSAOWP00000002065	ENSAOWP00000023039	annotation not available	SHC adaptor protein 3.	0.622
ENSAOWP00000013609	ENSAOWP00000020572	ENSAOWP00000013609	ENSAOWP00000020572	annotation not available	annotation not available	0.756
ENSAOWP00000013609	GRB2	ENSAOWP00000013609	ENSAOWP00000019098	annotation not available	Growth factor receptor bound protein 2.	0.874
ENSAOWP00000013609	IGF1R	ENSAOWP00000013609	ENSAOWP00000001541	annotation not available	Insulin like growth factor 1 receptor.	0.872
ENSAOWP00000013609	PTPN1	ENSAOWP00000013609	ENSAOWP00000001839	annotation not available	Protein tyrosine phosphatase non-receptor type 1.	0.406
ENSAOWP00000013609	SHC1	ENSAOWP00000013609	ENSAOWP00000026467	annotation not available	SHC adaptor protein 1.	0.680
ENSAOWP00000013609	SHC3	ENSAOWP00000013609	ENSAOWP00000023039	annotation not available	SHC adaptor protein 3.	0.680
ENSAOWP00000020572	ENSAOWP00000013609	ENSAOWP00000020572	ENSAOWP00000013609	annotation not available	annotation not available	0.756
ENSAOWP00000020572	GRB2	ENSAOWP00000020572	ENSAOWP00000019098	annotation not available	Growth factor receptor bound protein 2.	0.874
ENSAOWP00000020572	IGF1R	ENSAOWP00000020572	ENSAOWP00000001541	annotation not available	Insulin like growth factor 1 receptor.	0.900
ENSAOWP00000020572	PIK3R1	ENSAOWP00000020572	ENSAOWP00000002788	annotation not available	Phosphoinositide-3-kinase regulatory subunit 1.	0.757
ENSAOWP00000020572	PTPN1	ENSAOWP00000020572	ENSAOWP00000001839	annotation not available	Protein tyrosine phosphatase non-receptor type 1.	0.406
ENSAOWP00000020572	SHC1	ENSAOWP00000020572	ENSAOWP00000026467	annotation not available	SHC adaptor protein 1.	0.736
ENSAOWP00000020572	SHC3	ENSAOWP00000020572	ENSAOWP00000023039	annotation not available	SHC adaptor protein 3.	0.680
GRB2	ENSAOWP00000002065	ENSAOWP00000019098	ENSAOWP00000002065	Growth factor receptor bound protein 2.	annotation not available	0.692
GRB2	ENSAOWP00000013609	ENSAOWP00000019098	ENSAOWP00000013609	Growth factor receptor bound protein 2.	annotation not available	0.874