STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TYK2Tyrosine kinase 2. (1186 aa)    
Predicted Functional Partners:
IFNAR1
Interferon alpha and beta receptor subunit 1.
   
 0.961
IL10RA
Interleukin 10 receptor subunit alpha.
   
 0.946
SOCS3
Suppressor of cytokine signaling 3.
   
 0.935
SOCS1
Suppressor of cytokine signaling 1.
   
 0.932
STAT3
Signal transducer and activator of transcription 3.
   
 0.929
IL6ST
Interleukin 6 signal transducer.
    
 0.923
ENSAOWP00000015880
annotation not available
    
 0.908
LEPR
Leptin receptor.
    
 0.907
ENSAOWP00000026293
annotation not available
   
 0.893
ENSAOWP00000013003
annotation not available
    
 0.890
Your Current Organism:
Apteryx owenii
NCBI taxonomy Id: 8824
Other names: A. owenii, little spotted kiwi
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.