STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTPN1Protein tyrosine phosphatase non-receptor type 1. (437 aa)    
Predicted Functional Partners:
INSR
Insulin receptor.
    
 0.938
IGF1R
Insulin like growth factor 1 receptor.
    
 0.894
INSRR
Insulin receptor related receptor.
    
 0.894
CTNNB1
Catenin beta 1.
    
 0.875
STAT3
Signal transducer and activator of transcription 3.
   
 0.859
SRC
SRC proto-oncogene, non-receptor tyrosine kinase.
   
 0.843
PTPN11
Protein tyrosine phosphatase non-receptor type 11.
   
0.842
ENSAOWP00000005991
annotation not available
   
0.842
JAK2
Janus kinase 2.
   
 0.819
JAK3
Janus kinase 3.
   
 0.819
Your Current Organism:
Apteryx owenii
NCBI taxonomy Id: 8824
Other names: A. owenii, little spotted kiwi
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.