STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HHIPHedgehog interacting protein. (696 aa)    
Predicted Functional Partners:
SHH
Sonic hedgehog signaling molecule.
    
 0.960
DHH
Desert hedgehog signaling molecule.
    
 0.951
IHH
Indian hedgehog signaling molecule.
    
 0.951
SORL1
Sortilin related receptor 1.
    
 0.789
PTCH1
Patched 1.
    
 
 0.659
ENSAOWP00000026022
annotation not available
     
 0.586
NCSTN
Nicastrin.
    
 0.576
GAPDH
Glyceraldehyde-3-phosphate dehydrogenase.
     
 0.560
SMO
Smoothened, frizzled class receptor.
    
 
 0.543
APBA1
Amyloid beta precursor protein binding family A member 1.
   
 
 0.529
Your Current Organism:
Apteryx owenii
NCBI taxonomy Id: 8824
Other names: A. owenii, little spotted kiwi
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.