STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1294 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
   
 0.994
PTPN11
Protein tyrosine phosphatase non-receptor type 11.
    
 0.939
ENSAOWP00000005991
annotation not available
    
 0.939
SHC1
SHC adaptor protein 1.
    
 0.935
SHC3
SHC adaptor protein 3.
    
 0.927
GAB1
GRB2 associated binding protein 1.
    
 0.918
FGFR3
Fibroblast growth factor receptor 3.
    
 0.914
GAB2
GRB2 associated binding protein 2.
     
 0.909
KRAS
KRAS proto-oncogene, GTPase.
   
 0.906
FGFR1
Fibroblast growth factor receptor 1.
    
 0.904
Your Current Organism:
Apteryx owenii
NCBI taxonomy Id: 8824
Other names: A. owenii, little spotted kiwi
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.