STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMAD1SMAD family member 1. (465 aa)    
Predicted Functional Partners:
SMAD4
SMAD family member 4.
   
0.992
SMURF1
SMAD specific E3 ubiquitin protein ligase 1.
    
 0.985
SMAD6
SMAD family member 6.
    
0.955
ACVR1
Activin A receptor type 1.
   
 0.932
LEMD3
LEM domain containing 3.
    
 
 0.927
BMPR2
Bone morphogenetic protein receptor type 2.
   
 0.925
ACVRL1
Activin A receptor like type 1.
   
 0.919
ENSAOWP00000017405
annotation not available
  
 
0.918
BMPR1B
Bone morphogenetic protein receptor type 1B.
   
 0.917
BMPR1A
Bone morphogenetic protein receptor type 1A.
   
 0.917
Your Current Organism:
Apteryx owenii
NCBI taxonomy Id: 8824
Other names: A. owenii, little spotted kiwi
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.