STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ROS1ROS proto-oncogene 1, receptor tyrosine kinase. (2305 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
    
 0.881
GAB1
GRB2 associated binding protein 1.
    
 0.807
CBLB
Cbl proto-oncogene B.
    
 0.769
CBL
Cbl proto-oncogene.
    
 0.769
PTN
Pleiotrophin.
    
 0.767
ENSAOWP00000003562
annotation not available
    
 0.718
TNS1
Tensin 1.
    
 0.718
ENSAOWP00000024361
annotation not available
    
 0.718
ITSN2
Intersectin 2.
   
 0.685
PIK3CA
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha.
    
 0.681
Your Current Organism:
Apteryx owenii
NCBI taxonomy Id: 8824
Other names: A. owenii, little spotted kiwi
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.