STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGR1Early growth response 1. (510 aa)    
Predicted Functional Partners:
CREBBP
CREB binding protein.
    
 0.871
EP300
E1A binding protein p300.
    
 0.858
MAPK7
Mitogen-activated protein kinase 7.
   
 0.824
MAPK1
Mitogen-activated protein kinase 1.
   
 0.824
FOS
Fos proto-oncogene, AP-1 transcription factor subunit.
   
 0.750
JUN
Jun proto-oncogene, AP-1 transcription factor subunit.
   
 0.714
NAB1
NGFI-A binding protein 1.
    
 0.696
FOSB
FosB proto-oncogene, AP-1 transcription factor subunit.
   
 0.606
BARD1
BRCA1 associated RING domain 1.
    
  0.580
MYSM1
Myb like, SWIRM and MPN domains 1.
   
  0.572
Your Current Organism:
Apteryx owenii
NCBI taxonomy Id: 8824
Other names: A. owenii, little spotted kiwi
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.