STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DvMF_0027TIGRFAM: indolepyruvate/phenylpyruvate decarboxylase; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: dde:Dde_2331 putative phenylpyruvate decarboxylase. (572 aa)    
Predicted Functional Partners:
DvMF_2633
PFAM: Aldehyde Dehydrogenase_; KEGG: dsy:DSY1102 hypothetical protein.
   
 0.918
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
     
 0.645
DvMF_0013
Fructose-1,6-bisphosphate aldolase, class II; KEGG: dde:Dde_2341 fructose-bisphosphate aldolase; TIGRFAM: ketose-bisphosphate aldolase; fructose-1,6-bisphosphate aldolase, class II; PFAM: ketose-bisphosphate aldolase class-II.
   
  
 0.511
pgk
PFAM: phosphoglycerate kinase; KEGG: aeh:Mlg_2842 phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
   
  
 0.511
DvMF_1564
Aminotransferase class I and II; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aminotransferase class I and II; KEGG: dde:Dde_0513 aminotransferase.
     
 0.507
DvMF_2322
PFAM: iron-containing alcohol dehydrogenase; Aldehyde Dehydrogenase_; KEGG: emi:Emin_0772 iron-containing alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
 0.496
ilvD
KEGG: dde:Dde_0116 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family.
  
 
 
 0.491
DvMF_0358
PFAM: CBS domain containing protein; phosphoesterase RecJ domain protein; Polynucleotide adenylyltransferase region; phosphoesterase DHHA1; KEGG: dde:Dde_1972 CBS; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
   
   0.457
DvMF_0413
Putative signal transduction protein with CBS domains; PFAM: CBS domain containing protein; KEGG: dde:Dde_2078 CBS.
   
   0.457
DvMF_1585
PFAM: CBS domain containing protein; KEGG: dde:Dde_0765 CBS.
   
   0.457
Your Current Organism:
Desulfovibrio vulgaris Miyazaki
NCBI taxonomy Id: 883
Other names: D. vulgaris str. 'Miyazaki F', Desulfovibrio vulgaris (strain Miyazaki), Desulfovibrio vulgaris str. 'Miyazaki F'
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