Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DvMF_0151PFAM: protein of unknown function DUF167; KEGG: dde:Dde_2170 hypothetical protein; Belongs to the UPF0235 family. (106 aa)    
Predicted Functional Partners:
DvMF_0149
PFAM: protein of unknown function YGGT; KEGG: lip:LI0363 predicted integral membrane protein.
  
  
 0.844
DvMF_0150
PFAM: DivIVA family protein; KEGG: dde:Dde_2171 cell-division initiation protein DivIVA.
  
  
 0.843
DvMF_0152
KEGG: dde:Dde_2169 hypothetical protein.
       0.753
DvMF_0153
KEGG: dde:Dde_2168 acetolactate synthase, large subunit; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein.
       0.745
DvMF_0154
TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; acetolactate synthase small subunit; KEGG: dde:Dde_2167 acetolactate synthase 3 regulatory subunit.
       0.736
DvMF_0148
TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: dde:Dde_2173 HAD family hydrolase.
       0.558
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
       0.502
DvMF_0147
KEGG: dde:Dde_2174 hypothetical protein.
       0.442
DvMF_0146
KEGG: dde:Dde_2175 hypothetical protein.
       0.439
DvMF_0206
KEGG: dde:Dde_1679 hypothetical protein.
 
     0.412
Your Current Organism:
Desulfovibrio vulgaris Miyazaki
NCBI taxonomy Id: 883
Other names: D. vulgaris str. 'Miyazaki F', Desulfovibrio vulgaris (strain Miyazaki), Desulfovibrio vulgaris str. 'Miyazaki F'
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