STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hydBNickel-dependent hydrogenase large subunit; Catalyzes the reversible oxidoreduction of molecular hydrogen, in conjunction with a specific electron acceptor, cytochrome c3. (567 aa)    
Predicted Functional Partners:
hydA
Hydrogenase (NiFe) small subunit HydA; Catalyzes the reversible oxidoreduction of molecular hydrogen, in conjunction with a specific electron acceptor, cytochrome c3.
 
 
 0.999
DvMF_2895
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; methyl-viologen-reducing hydrogenase delta subunit; KEGG: dde:Dde_1112 heterodisulfide reductase, iron-sulfur-binding subunit, putative.
  
 
 0.973
DvMF_1732
KEGG: dde:Dde_3755 hydrogenase (NiFe) small subunit (HydA); TIGRFAM: hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit.
 
 
 0.967
hysA
KEGG: dde:Dde_2134 hydrogenase (NiFe) small subunit (HydA); TIGRFAM: hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit.
 
 
 0.958
DvMF_0269
TIGRFAM: hydrogenase maturation protease; hydrogenase expression/formation protein; PFAM: peptidase M52 hydrogen uptake protein; KEGG: dde:Dde_2139 hydrogenase expression/formation protein.
 
 
 0.931
DvMF_0272
TIGRFAM: hydrogenase maturation protease; PFAM: peptidase M52 hydrogen uptake protein; KEGG: dde:Dde_2136 peptidase M52, hydrogen uptake protein.
 
 
 0.880
DvMF_0325
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; methyl-viologen-reducing hydrogenase delta subunit; KEGG: dde:Dde_3528 hydrogenase, iron-sulfur cluster-binding subunit, putative.
  
 
 0.855
DvMF_1860
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate:ferredoxin (flavodoxin) oxidoreductase; KEGG: dde:Dde_3237 pyruvate:ferredoxin (flavodoxin) oxidoreductase; Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
  
  
 0.827
hypA
Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.787
DvMF_1868
PFAM: protein of unknown function DUF162; protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: dde:Dde_3245 iron-sulfur cluster-binding protein.
  
 
 0.781
Your Current Organism:
Desulfovibrio vulgaris Miyazaki
NCBI taxonomy Id: 883
Other names: D. vulgaris str. 'Miyazaki F', Desulfovibrio vulgaris (strain Miyazaki), Desulfovibrio vulgaris str. 'Miyazaki F'
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